Results 61 to 70 of about 2,622 (152)
eFood, Volume 7, Issue 2, April 2026.Red ginseng (RG)–Lycium ruthenicum (LR)–Ganoderma lucidum (GL) compound formula synergistically alleviates fatigue by modulating muscle contraction, enhancing energy metabolism and attenuating oxidative stress. ABSTRACT Many plant and fungal extracts (PFEs) show anti‐fatigue properties through various pathways, but synergistic formulas and mechanisms ...
Tao Liu +13 more
wiley +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.N6‐methyladenosine RNA methylation regulators are intricately linked with the development of polycystic ovary syndrome (PCOS) and may influence immune cell infiltration in affected individuals. This study enhances our understanding of the molecular interactions in PCOS and suggests potential biomarkers for diagnosis and targets for therapeutic ...
Wenting Xu +8 more
wiley +1 more source
Iron overload in hereditary spherocytosis: Are genetic factors the cause?
British Journal of Haematology, Volume 208, Issue 2, Page 691-696, February 2026.Summary Non‐transfusional iron overload (IOL) in hereditary spherocytosis (HS) is poorly documented compared with other red blood cell disorders. We studied 13 HS adults with confirmed IOL to identify potential genetic factors. Using a next‐generation sequencing panel of 46 genes related to HS, anaemia and iron metabolism, we found no association ...
Lucie Donaty +6 more
wiley +1 more source
The biology of PKM2 in the metabolism and senescence in diabetic kidney disease
Journal of Diabetes Investigation, Volume 17, Issue 2, Page 197-204, February 2026.ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley +1 more source
Anemia, Volume 2026, Issue 1, 2026.Background Malaria remains a major global health burden, with red blood cell (RBC) polymorphisms conferring partial protection. However, the epistatic interactions among co‐inherited RBC polymorphisms are poorly understood. We aimed to characterise how epistatic interactions among malaria‐protective RBC polymorphisms modify risk across the infection‐to‐
George Paasi +11 more
wiley +1 more source
Blood, 2015 Abstract Red blood cell pyruvate kinase deficiency (PKD) is the most frequent enzyme abnormality of the glycolytic pathway and the most common cause of hereditary nonspherocytic hemolytic anemia. Its incidence has been estimated to be 1 in 20,000, especially in regions where consanguinity is common. It is inherited in autosomal recessive
Harry Lesmana +8 more
openaire +1 more source
Metabolic Responses to Cyclic Fasting in Juvenile Turbot (Scophthalmus maximus)
Aquaculture Nutrition, Volume 2026, Issue 1, 2026.Feed accounts for the majority of aquaculture production costs, making strategies that reduce feed input without compromising growth economically attractive. This 72‐day study evaluated the effects of cyclic fasting regimens on growth, body composition, and liver transcriptome in juvenile turbot (initial body weight 5.54 g).
Haiyan Xiong +9 more
wiley +1 more source
Frontiers in Endocrinology, 2020 Carbohydrate response element-binding protein (ChREBP) plays an important role in the development of type 2 diabetes, dyslipidemia, and non-alcoholic fatty liver disease, as well as tumorigenesis.
Katsumi Iizuka +5 more
doaj +1 more source
Pyruvate Kinase Deficiency: Current Challenges and Future Prospects
Journal of Blood Medicine, 2022 Bruno Fattizzo,1,2 Francesca Cavallaro,1,2 Anna Paola Maria Luisa Marcello,1 Cristina Vercellati,1 Wilma Barcellini1 1Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; 2Department of Oncology and Hemato-Oncology ...
Fattizzo B +4 more
doaj