Results 231 to 240 of about 60,739 (253)
Some of the next articles are maybe not open access.
Increased PKR level in human CADASIL brains
Virchows Archiv, 2018Cerebral autosomal dominant arteriolopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is the most common form of hereditary small vessel disease (SVD) of the brain. Neuronal apoptosis has been demonstrated in the cortex of patients.
Emmanuel Cognat +6 more
openaire +2 more sources
Science Signaling, 2011
A kinase involved in detecting viral RNA also enhances inhibitory neurotransmission in the brain.
openaire +1 more source
A kinase involved in detecting viral RNA also enhances inhibitory neurotransmission in the brain.
openaire +1 more source
pKR+ values for pyridinium cations
Tetrahedron, 1987Abstract Literature data for nucleophilic addition at C-4 of C-3 substituted 1-methylpyridinium cations are evaluated. It is shown that sufficient data are available to allow the confident evaluation of a linear free energy relationship for the equilibration of these cations with their C-4 hydroxide adducts (pseudobases) in aqueous solution: pKR ...
openaire +1 more source
Trends in Biochemical Sciences, 1995
The double-stranded RNA (dsRNA)-activated protein kinase, now called PKR, was first discovered by virtue of its ability to phosphorylate translation initiation factor eIF-2 and inhibit its activity. Recent studies have shown that expression of inactive mutants of PKR in cultured cells causes them to acquire characteristics typical of transformed cells.
openaire +2 more sources
The double-stranded RNA (dsRNA)-activated protein kinase, now called PKR, was first discovered by virtue of its ability to phosphorylate translation initiation factor eIF-2 and inhibit its activity. Recent studies have shown that expression of inactive mutants of PKR in cultured cells causes them to acquire characteristics typical of transformed cells.
openaire +2 more sources
[Cloning and expression of PKR gene and affinity purification of PKR interacting proteins].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2012To clone and express protein kinase regulated by double-stranded RNA (PKR) gene, and to purify and isolate PKR interacting proteins.By using specific primers, PKR gene fragments tagged with HA and FLAG (FLAG-PKR-HA, and HA-PKR-FLAG) were amplified by PCR, and cloned into pSG5 vector. The recombinant plasmids were transfected into PKR knockdown (PKR(
Jiong, Xie +6 more
openaire +1 more source
Progress in Nuclear Magnetic Resonance Spectroscopy, 2007
Darrin A. Lindhout +4 more
openaire +1 more source
Darrin A. Lindhout +4 more
openaire +1 more source