Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Antarctic place names newly decided by the Antarctic Place-Names Committee of Japan in 1981
Antarctic Record, 1982 The Antarctic Place-Names Committee of Japan worked out 38 new place names, which were officially approved by the Japanese Antarctic Research Expedition Headquarters, under date of 24th November 1981.
National Institute of Polar Research
doaj +1 more source
, 1912 Correcciones al artículo de Vinson sobre la toponimia vasca. Se hace un estudio de la toponimia de Iparralde sobre todo, basándose en documentos, cartas y otras fuentesCorrections to the article of Vinson on Basque place-names.
Jaurgain, Jean de
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Correction: Influence of palliative care policy on place of death for people with different cancer types: a nationwide' register study. [PDF]
PLoS OneÖhlén J +7 more
europepmc +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Espeleotoponímia de motivació paleontològica i antracotoponímia de les Illes Balears [PDF]
, 2010 [cat] En aquest treball es recopilen i estudien, des d’una perspectiva etnopaleontològica, les aportacions i influencies exercides pels fòssils en relació al patrimoni onomàstic toponímic relacionat amb cavitats càrstiques de l’àmbit geogràfic ...
Astudillo, Heracli +3 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Georgraphy of language groups around Fleurieu Peninsula at first contact [PDF]
, 2017 The place-names recorded at first contact (i.e. from the beginning of contact up to about 1850) show a clear demarcation of language between the lands northwest and southeast of the range at that time: Kaurna language to the northwest,1 and Ramindjeri ...
Schultz, Chester
core