Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Antarctic Place Names Newly Decided by the Antarctic Place-Names Committee of Japan in 1979
Antarctic Record, 1979 The Antarctic Place-Names Committee of Japan worked out 41 new place names, which were officially approved by the Japanese Antarctic Research EX-pedition Headquarters, under date of 22nd March 1979.
National Institute of Polar Research
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
ASAL-MUASAL NGARAN PATEMPATAN DI KACAMATAN CIMALAKA KABUPATEN SUMEDANG PIKEUN BAHAN PANGAJARAN DONGÉNG DI KELAS VII SMP [PDF]
, 2017 Penelitian ini bertujuan untuk mendeskripsikan asal-usul nama tempat, pola pemberian nama tempat yang ada di Kecamatan Cimalaka Kabupaten Sumedang dan bahan ajar dongeng di SMP kelas VII. Penelitian ini menggunakan metode kualitatif deskriptif. Adapun
Rifandi, Dede
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Correction: Influence of palliative care policy on place of death for people with different cancer types: a nationwide' register study. [PDF]
PLoS OneÖhlén J +7 more
europepmc +3 more sources
The Georgraphy of language groups around Fleurieu Peninsula at first contact [PDF]
, 2017 The place-names recorded at first contact (i.e. from the beginning of contact up to about 1850) show a clear demarcation of language between the lands northwest and southeast of the range at that time: Kaurna language to the northwest,1 and Ramindjeri ...
Schultz, Chester
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Espeleotoponímia de motivació paleontològica i antracotoponímia de les Illes Balears [PDF]
, 2010 [cat] En aquest treball es recopilen i estudien, des d’una perspectiva etnopaleontològica, les aportacions i influencies exercides pels fòssils en relació al patrimoni onomàstic toponímic relacionat amb cavitats càrstiques de l’àmbit geogràfic ...
Astudillo, Heracli +3 more
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