Results 81 to 90 of about 17,689,950 (324)

Place Cells in Perspective [PDF]

open access: yesNeuron, 2008
The importance of the hippocampus for learning and memory was first recognized in the late 1950s when William Scoville and Brenda Milner published their account of patient H.M. whose hippocampus was removed during an operation aimed at treating his otherwise intractable epilepsy.
openaire   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Slowness and Sparseness Lead to Place, Head-Direction, and Spatial-View Cells [PDF]

open access: yes, 2007
We present a model for the self-organized formation of place cells, head-direction cells, and spatial-view cells in the hippocampal formation based on unsupervised learning on quasi-natural visual stimuli.
Franzius, Mathias   +2 more
core  

Polar catastrophe and electronic reconstructions at the LaAlO3/SrTiO3 interface: evidence from optical second harmonic generation

open access: yes, 2009
The so-called "polar catastrophe", a sudden electronic reconstruction taking place to compensate for the interfacial ionic polar discontinuity, is currently considered as a likely factor to explain the surprising conductivity of the interface between the
A. Savoia   +11 more
core   +2 more sources

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi   +4 more
wiley   +1 more source

Firing rate adaptation affords place cell theta sweeps, phase precession, and procession

open access: yeseLife
Hippocampal place cells in freely moving rodents display both theta phase precession and procession, which is thought to play important roles in cognition, but the neural mechanism for producing theta phase shift remains largely unknown.
Tianhao Chu   +8 more
doaj   +1 more source

A hierarchical anti-Hebbian network model for the formation of spatial cells in three-dimensional space. [PDF]

open access: yes, 2018
Three-dimensional (3D) spatial cells in the mammalian hippocampal formation are believed to support the existence of 3D cognitive maps. Modeling studies are crucial to comprehend the neural principles governing the formation of these maps, yet to date ...
Chakravarthy, Srinivasa   +2 more
core   +3 more sources

Path integration in place cells of developing rats

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance The mammalian brain has neurons that specifically represent the animal’s location in the environment. Place cells in the hippocampus encode position, whereas grid cells in the medial entorhinal cortex, one synapse away, also express ...
T. Bjerknes   +3 more
semanticscholar   +1 more source

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost   +10 more
wiley   +1 more source

Synchronous ensembles of hippocampal CA1 pyramidal neurons during novel exploration

open access: yeseLife
Synchronous neuronal ensembles play a pivotal role in the consolidation of long-term memory in the hippocampus. However, their organization during the acquisition of spatial memory remains less clear.
En-Li Chen   +3 more
doaj   +1 more source

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