Results 71 to 80 of about 881,114 (263)

The role and place of planning in crisis management

open access: yesУченые записки Российской академии предпринимательства, 2021
In article is considered specifics of planning in the conditions of crisis management, are submitted the short analysis of the enterprises which faced crisis in the Kaluga region.
E. V. Emeljanova
doaj  

Managing the Market Place: The Consortium Approach

open access: yesSerials: The Journal for the Serials Community, 1997
The funding context of higher\ud education is examined, together\ud with some of the constraints and\ud imperatives to which it gives rise.\ud The history, constitution and\ud operation of the Southern\ud Universities Purchasing\ud Consortium's Libraries Project\ud Group are discussed.
Ball, David, Wright, Susan
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

INTRAUTERINE INSEMINATION: CURRENT PLACE IN INFERTILITY MANAGEMENT

open access: yesEuropean Medical Journal, 2018
Infertility has become a significant problem worldwide. Multiple management options are available nowadays, which include intrauterine insemination (IUI), in vitro fertilisation (IVF), and intracytoplasmic sperm injection.
Shikha Jain
doaj  

Fractional Grey Breakpoint Model for Forecasting PM2.5 Under Energy Policy Shock

open access: yesFractal and Fractional
Traditional fossil fuel consumption is the main contributor increased atmospheric PM2.5 concentration. In 2014, China designated 81 new-energy demonstration cities, aiming to replace traditional fossil fuel energy with renewable energy.
Haolei Gu, Yuchen Wang, Tongyang Yang
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Place management in off-premise alcohol outlets: Results of a multi-methods study in a six-city California area. [PDF]

open access: yesInt J Drug Policy, 2020
Ghanem L   +5 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

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