Results 111 to 120 of about 5,011,952 (310)
Place management in off-premise alcohol outlets: Results of a multi-methods study in a six-city California area. [PDF]
Int J Drug Policy, 2020 Ghanem L +5 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
THE VALUE OF KM IN REFORMING THE SOCIETY [PDF]
Knowledge management is evolving from being successful on small companies to the entire society. The era of information technology and the speed the changes take place, imply a profound transformation from tactic to strategic level, where decision-makers
Tache JURUBESCU
core
, 2016 The fourth International Conference on Management of Natural Resources, Sustainable Development and Ecological Hazards (RAVAGE for short) took place in Opatija, Croatia, organised by the Wessex Institute (WIT), represented by its Director, Professor ...
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Romanian Economic Journal, 2016 Confronted with a variety of political risks that affect their international activities, multinational corporations (MNCs) can use Political Risk Insurance (PRI) as a method to mitigate some of those risks.
Violeta Iftinchi , Gheorghe Hurduzeu
doaj
An analysis of the quality and operational efficiency of the Crest Clean franchise [PDF]
, 2018 In the commercial cleaning business, quality and hygiene of the workplace plays a very significant role. This research aims to analyse the existing operational process and cleaning quality of the cleaning services delivered at Centre Place, Hamilton from
Harnett, Denise, Selvaraj, Sethuram
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Application of Weather Derivatives in Multi-Period Risk Management [PDF]
This work is a first attempt to analyze the effect of weather derivative availability on the risk management strategies in a multi-period setting, when crop activities take place twice a year. Rice production in Ecuador is used as a case study. Numerical
Sanchez, Leonardo, Vedenov, Dmitry V.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source