Results 91 to 100 of about 12,798,938 (311)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

INTRAUTERINE INSEMINATION: CURRENT PLACE IN INFERTILITY MANAGEMENT

open access: yesEuropean Medical Journal, 2018
Infertility has become a significant problem worldwide. Multiple management options are available nowadays, which include intrauterine insemination (IUI), in vitro fertilisation (IVF), and intracytoplasmic sperm injection.
Shikha Jain
doaj  

Fractional Grey Breakpoint Model for Forecasting PM2.5 Under Energy Policy Shock

open access: yesFractal and Fractional
Traditional fossil fuel consumption is the main contributor increased atmospheric PM2.5 concentration. In 2014, China designated 81 new-energy demonstration cities, aiming to replace traditional fossil fuel energy with renewable energy.
Haolei Gu, Yuchen Wang, Tongyang Yang
doaj   +1 more source

Place management in off-premise alcohol outlets: Results of a multi-methods study in a six-city California area. [PDF]

open access: yesInt J Drug Policy, 2020
Ghanem L   +5 more
europepmc   +1 more source

Instructor interview for Place-Based WAC/WID writing instruction in Management, clip 4 of 13

open access: yes, 2015
This item includes a segment of an instructor interview in a Writing Intensive course in Management at the University of Hawaiʻi at Mānoa. The interview was conducted in 2013, and in this clip the interviewee is responding to the question 'What ...
Place-based WAC/WID Hui
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Eustress and distress : their interpretation in stress management interventions, and implications for research, practice, and education

open access: yes, 2004
We examine the place of stress, distress, and eustress in the practice of stress management interventions. The concept of stress seems to have been largely ignored in the occupational stress, and stress management literature.
Kolt, Gregory S.   +2 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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