Results 91 to 100 of about 12,798,938 (311)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
INTRAUTERINE INSEMINATION: CURRENT PLACE IN INFERTILITY MANAGEMENT
Infertility has become a significant problem worldwide. Multiple management options are available nowadays, which include intrauterine insemination (IUI), in vitro fertilisation (IVF), and intracytoplasmic sperm injection.
Shikha Jain
doaj
Fractional Grey Breakpoint Model for Forecasting PM2.5 Under Energy Policy Shock
Traditional fossil fuel consumption is the main contributor increased atmospheric PM2.5 concentration. In 2014, China designated 81 new-energy demonstration cities, aiming to replace traditional fossil fuel energy with renewable energy.
Haolei Gu, Yuchen Wang, Tongyang Yang
doaj +1 more source
Place management in off-premise alcohol outlets: Results of a multi-methods study in a six-city California area. [PDF]
Ghanem L +5 more
europepmc +1 more source
Instructor interview for Place-Based WAC/WID writing instruction in Management, clip 4 of 13
This item includes a segment of an instructor interview in a Writing Intensive course in Management at the University of Hawaiʻi at Mānoa. The interview was conducted in 2013, and in this clip the interviewee is responding to the question 'What ...
Place-based WAC/WID Hui
core
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
We examine the place of stress, distress, and eustress in the practice of stress management interventions. The concept of stress seems to have been largely ignored in the occupational stress, and stress management literature.
Kolt, Gregory S. +2 more
core
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source

