Results 101 to 110 of about 13,445,444 (307)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Fractional Grey Breakpoint Model for Forecasting PM2.5 Under Energy Policy Shock
Fractal and FractionalTraditional fossil fuel consumption is the main contributor increased atmospheric PM2.5 concentration. In 2014, China designated 81 new-energy demonstration cities, aiming to replace traditional fossil fuel energy with renewable energy.
Haolei Gu, Yuchen Wang, Tongyang Yang
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Place of effective management test in the income tax act, 1961: is it the right way forward? [PDF]
, 2015 The Finance Act, 2015 amended §6(3)(ii) of the Income Tax Act, 1961 to introduce a new test for determining the residential status of companies. The new test is called the ‘Place of Effective Management’ test for interpretation of which, the Central ...
Kotha, Ashrita Prasad
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
, 2015 This paper develops a critical assessment of a marketing practitioner’s activities in her attempt to foster a pubic debate in Rio de Janeiro about the need of a more rigorous city brand management strategy.
Raquel Goulart Sztejnberg +1 more
core +1 more source
Crossing the canyon of change: Lessons for leading healthcare innovation
Future Healthcare JournalHealthcare is entering an era of rapid technological advancement, yet history reminds us that technologies rarely transform care through technical excellence alone.
Sabah Janjua, Jonathan Benger
doaj +1 more source
Conceptualising place branding in three approaches:towards a new definition of place brands as embodied experiences [PDF]
Purpose: This paper aims to provide conceptual clarity on the different approaches of place branding in the literature. It discusses three main approaches and provides a new definition of place brands that acknowledges the full multi-sensory experience ...
Eshuis, J +3 more
core +1 more source