Results 71 to 80 of about 1,071,106 (310)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

'Place' and sustainability: Research opportunities and dilemmas

open access: yes, 1997
Place, as the centre of peoples’ experiences and lives, has become a focus in natural resource management in the 1990s. Efforts have and are being made to consider place in forest, national park and farm management, and in managing resource uses such as ...
Moore, S.A.
core   +1 more source

Is the Asset Transfer of Public Leisure Facilities in England an Example of Associative Democracy?

open access: yesAdministrative Sciences, 2015
In England, public sports facilities and libraries provided by local government are being transferred to management and delivery by volunteers. The catalyst for this development has been reductions in local government budgets.
Geoff Nichols   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Are social commerce websites capable of increasing the Town Centre value?

open access: yes, 2013
The purpose of this paper is to analyse the perception that people (citizens, tourists and investors) have regarding Town Centre revitalization problems.
CABONI, FEDERICA, GIUDICI, ERNESTINA
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Understanding the place attachement of campers along the southern Ningaloo Coast, Australia

open access: yes, 2012
Place attachment and place related concepts were developed to examine bonds individuals form with places. Place concepts have been adopted by managers of natural areas to help refine their understanding of visitor preferences.
Tonge, Joanna
core   +1 more source

The Place of Oral History in Archives Management [PDF]

open access: yesتحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2008
Purpose: This paper considers the concept and background of oral history in internal and external references. Also it studies necessity, importance and agents of arising and developing oral history in the field of archives.
Majid Sabzipoor
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Eustress and distress : their interpretation in stress management interventions, and implications for research, practice, and education

open access: yes, 2004
We examine the place of stress, distress, and eustress in the practice of stress management interventions. The concept of stress seems to have been largely ignored in the occupational stress, and stress management literature.
Kolt, Gregory S.   +2 more
core  

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