Results 91 to 100 of about 1,071,106 (310)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2015 This paper develops a critical assessment of a marketing practitioner’s activities in her attempt to foster a pubic debate in Rio de Janeiro about the need of a more rigorous city brand management strategy.
Raquel Goulart Sztejnberg +1 more
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A Place for Nurses in Health Service Management?
Nursing Praxis in Aotearoa New Zealand, 1989 Professional advice is a load of hogwash ...'So says an anonymous regional manager of the British National health Service (NHS) in an interview reported by researchers Philip Strong and Jane Robinson in the September 1988 issue of the Nursing Times.
Joy Bickley RGON
doaj
From Networking to Attitudinal Outcomes: Psychological Capital as a Mediator
Psychologica BelgicaBuilding on conservation of resources (COR) theory and following recent recommendations, this study investigates the mediating role of Psychological Capital (PsyCap) in the relationships between networking behaviors and attitudinal outcomes (i.e., work ...
Rachel Huynen +4 more
doaj +1 more source
The role and place of planning in crisis management
Ученые записки Российской академии предпринимательства, 2021 In article is considered specifics of planning in the conditions of crisis management, are submitted the short analysis of the enterprises which faced crisis in the Kaluga region.
E. V. Emeljanova
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The evolutionary ‘waves’ of place-shaping: pre, during and post recession
, 2011 This paper is concerned with the evolution of place-shaping over the past decade or so and its potential future direction, specifically relating to a UK context but with varying aspects of resonance internationally.
Pugalis, L, Pugalis, Lee
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Improving network management efficiency : knowledge level granulation and fuzzy representation
, 2010 Modern system management needs the capabilities to deal with a combination of areas, ranging from administration of elements to provision of services and management of the enterprise itself. As such, traditional element-based network management views are
Shahrestani, Seyed A. (R10567)
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