Results 251 to 260 of about 677,625 (318)

Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students. [PDF]

J Int Soc Sports Nutr
Gong Z, Yu S, Lyu Z, Huang W, Zhang T.
europepmc   +1 more source

Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate a set of pharmacodynamic biomarkers reflecting acute, delayed and sustained central nervous system effects of S‐ketamine, used as a tool compound for rapid‐acting antidepressant activity, with the goal of informing biomarker strategies for delayed antidepressant effects.
Catherine M. K. E. de Cuba, Annika A. de Goede, Joost. C. van Mechelen, Laura G. J. M. Borghans, Liam van der Aa, Erik Olofsen, Maria J. Juachon, Robert J. Doll, Amy Gillespie, Catherine J. Harmer, Gabriël E. Jacobs, Jules A. A. C. Heuberger   +11 more
wiley   +1 more source

Effects of antidepressant medications on brain tissue microstructure in persistent depressive disorder across two randomized controlled trials. [PDF]

Neuroimage Clin
Bansal R, Hellerstein DJ, Sawardekar S, Chen Y, Peterson BS.   +4 more
europepmc   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Midodrine versus placebo in patients with acute-on-chronic liver failure with ascites-A randomized trial (MIDAS trial). [PDF]

Hepatol Commun
Kulkarni AV, Venishetty S, Prasanna S, Iyengar S, Sarada SV, Premkumar M, Sharma M, Alla M, Rao PN, Reddy DN, Reddy KR.   +10 more
europepmc   +1 more source

Efficacy and safety of clobetasol propionate ophthalmic nanoemulsion for treating intraocular inflammation and pain associated with cataract surgery: two phase 3 multicentre, randomised, placebo-controlled, double-masked clinical studies. [PDF]

BMJ Open
Schwartz A, Wellish K, Zaman F, Jong K, Sadri E, Martel J, Peace J, Korenfeld M.   +7 more
europepmc   +1 more source

The Placebo Effect in Rare Disease Clinical Trials: Measurement, Impact, and Statistical Approaches for Patient-as-Own-Control Designs. [PDF]

Clin Transl Sci
Summar ML, Woodcock J.
europepmc   +1 more source

The effect of fecal microbiota transplantation on quality of life in patients with chronic pouchitis: a post hoc analysis of the MicroPouch trial. [PDF]

Ther Adv Gastroenterol
Jakobsen SS, Kousgaard SJ, Cold F, Halkjær SI, Petersen AM, Kjeldsen J, Hansen JM, Thorlacius-Ussing O.   +7 more
europepmc   +1 more source

Time to accelerate rare disease research: AI‐powered in silico trials, digital twin‐driven RCTs and decision‐grade real‐world evidence

British Journal of Clinical Pharmacology, EarlyView.
Andrej Belančić, Elvira Meni Maria Gkrinia, Oscar Della Pasqua, Reecha Sofat, Dinko Vitezić, Robert Likić   +5 more
wiley   +1 more source

Effect of atropine on time to cardiac arrest in hypoxic bradycardia: a randomised cross-over study in a porcine apnoea model. [PDF]

BJA Open
Pařízek T, Waldauf P, Kalina M, Kurzová Z, Odstrčilová I, Hunák J, Freml J, Dvořák R, Peřan D, Vlková A, Duška F.   +10 more
europepmc   +1 more source