Results 21 to 30 of about 1,365,991 (387)

Placebo and Non-specific Effects in Reconsolidation-Based Treatment for Arachnophobia

Frontiers in Psychiatry, 2021
The idea that maladaptive memories may be rendered susceptible to interference after reactivation raises the possibility of reactivating and neutralizing clinically-relevant emotional memories.
James W. B. Elsey, Merel Kindt
doaj   +1 more source

Lack of Effects of the Presence of a Dog on Pain Perception in Healthy Participants—A Randomized Controlled Trial

Frontiers in Pain Research, 2021
Animal-assisted interventions (AAIs) have been shown to be effective in the treatment of pain. Studies suggest that relationships with animals can have comparable qualities to relationships with humans and that this enables animals to provide social ...
Cora Wagner, Jens Gaab, Cosima Locher, Cosima Locher, Cosima Locher, Karin Hediger, Karin Hediger, Karin Hediger, Karin Hediger   +8 more
doaj   +1 more source

Updated Analysis From KEYNOTE-189: Pembrolizumab or Placebo Plus Pemetrexed and Platinum for Previously Untreated Metastatic Nonsquamous Non-Small-Cell Lung Cancer.

Journal of Clinical Oncology, 2020
PURPOSE In KEYNOTE-189, first-line pembrolizumab plus pemetrexed-platinum significantly improved overall survival (OS) and progression-free survival (PFS) compared with placebo plus pemetrexed-platinum in patients with metastatic nonsquamous non‒small ...
S. Gadgeel, D. Rodríguez-Abreu, G. Speranza, E. Esteban, E. Felip, M. Dómine, R. Hui, M. Hochmair, P. Clingan, S. Powell, Susanna Y. Cheng, H. Bischoff, N. Peled, F. Grossi, R. Jennens, M. Reck, E. Garon, S. Novello, B. Rubio-Viqueira, M. Boyer, T. Kurata, J. Gray, Jing Yang, T. Bas, M. Pietanza, M. Garassino   +25 more
semanticscholar   +1 more source

Effects of Coloring Food Images on the Propensity to Eat: A Placebo Approach With Color Suggestions

Frontiers in Psychology, 2020
BackgroundResearch findings on the appetite-enhancing effect of the color red and the appetite-reducing effect of blue have been inconsistent. The present study used a placebo approach and investigated whether verbal suggestions can enhance color ...
Carina Schlintl, Anne Schienle
doaj   +1 more source

Preoperative optimization of cardiac valve patients’ expectations: Study protocol of the randomized controlled ValvEx-trial

Frontiers in Cardiovascular Medicine, 2023
IntroductionComplete recovery after surgery depends on psychological factors such as preoperative information, expectations, and surgery-associated anxiety.
Nicole Horn, Laura Gärtner, Ardawan J. Rastan, Térezia B. Andrási, Juliane Lenz, Andreas Böning, Miriam Salzmann-Djufri, Ulrike Puvogel, Maria Genovese, Sibel Kus, Winfried Rief, Stefan Salzmann   +11 more
doaj   +1 more source

When a placebo is not a ‘placebo’: a placebo effect on postprandial glycaemia [PDF]

British Journal of Clinical Pharmacology, 2007
What is already known about this subject • Although placebo effects have been shown on subjective continuous variables such as pain, placebo effects on objective continuous variables remain uncertain.• The present, pilot, follow‐up investigation represents the first to assess a placebo effect on the objective continuous measurement of acute ...
Vladimir Vuksan, Anamaria Dascalu, Adish Ezatagha, John L. Sievenpiper   +3 more
openaire   +3 more sources

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma

New England Journal of Medicine, 2018
Background The programmed death 1 (PD‐1) inhibitor pembrolizumab has been found to prolong progression‐free and overall survival among patients with advanced melanoma.
A. Eggermont, C. Blank, M. Mandalà, G. Long, V. Atkinson, S. Dalle, A. Haydon, M. Lichinitser, A. Khattak, M. Carlino, S. Sandhu, J. Larkin, S. Puig, P. Ascierto, P. Rutkowski, D. Schadendorf, R. Koornstra, L. Hernandez-Aya, M. Maio, A. V. D. van den Eertwegh, J. Grob, R. Gutzmer, R. Jamal, P. Lorigan, N. Ibrahim, S. Marréaud, A. V. van Akkooi, S. Suciu, C. Robert   +28 more
semanticscholar   +1 more source

Pembrolizumab or Placebo Plus Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer: Randomized, Double-Blind, Phase III KEYNOTE-604 Study.

Journal of Clinical Oncology, 2020
PURPOSE Pembrolizumab monotherapy has shown antitumor activity in patients with small-cell lung cancer (SCLC). The randomized, double-blind, phase III KEYNOTE-604 study compared pembrolizumab plus etoposide and platinum (EP) with placebo plus EP for ...
C. Rudin, M. Awad, A. Navarro, M. Gottfried, S. Peters, T. Csőszi, P. Cheema, D. Rodríguez-Abreu, M. Wollner, J. Yang, J. Mazières, F. Orlandi, A. Luft, M. Gumus, T. Kato, G. Kalemkerian, Yi Luo, V. Ebiana, M. Pietanza, H. R. Kim, Keynote Investigators   +20 more
semanticscholar   +1 more source

The effect of placebo and neurophysiological involvements [PDF]

, 2004
Placebo and placebo effect are important issues related to the drug therapy for clinical and scientific meanings. The rates of placebo may get as many as 50% for analgesic drugs in headache. The high answer to placebo brings questions on pathophysiology
Galli, Federica, Guidetti, Vincenzo, Riccio, B.   +2 more
core   +1 more source

Open-label versus double-blind placebo treatment in irritable bowel syndrome: study protocol for a randomized controlled trial

Trials, 2017
Background Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration of placebo in randomized controlled trials (RCTs) and in clinical settings has been ...
Sarah Ballou, Ted J. Kaptchuk, William Hirsch, Judy Nee, Johanna Iturrino, Kathryn T. Hall, John M. Kelley, Vivian Cheng, Irving Kirsch, Eric Jacobson, Lisa Conboy, Anthony Lembo, Roger B. Davis   +12 more
doaj   +1 more source