Results 21 to 30 of about 888,393 (367)
Sham Acupuncture Is Not Just a Placebo
Journal of Acupuncture & Meridian Studies, 2022 Sham acupuncture should have two distinct features: first, it must be morphologically similar to verum acupuncture for blinding purposes, and second, it must not exert physiologically expected effects of verum acupuncture.
Tae-Hun Kim +2 more
doaj +1 more source
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis.
New England Journal of Medicine, 2006 BACKGROUND Natalizumab is the first alpha4 integrin antagonist in a new class of selective adhesion-molecule inhibitors. We report the results of a two-year phase 3 trial of natalizumab in patients with relapsing multiple sclerosis.
C. Polman +13 more
semanticscholar +1 more source
The Placebo Effect of Artificial Intelligence in Human-Computer Interaction [PDF]
, 2022 In medicine, patients can obtain real benefits from a sham treatment. These benefits are known as the placebo effect. We report two experiments (Experiment I: N=369; Experiment II: N=100) demonstrating a placebo effect in adaptive interfaces. Participants were asked to solve word puzzles while being supported by no system or an adaptive AI interface ...
arxiv +1 more source
Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis.
New England Journal of Medicine, 2010 BACKGROUND Nonalcoholic steatohepatitis is a common liver disease that can progress to cirrhosis. Currently, there is no established treatment for this disease.
A. Sanyal +15 more
semanticscholar +1 more source
An Evolutionary Perspective on Pain Communication
Evolutionary Psychology, 2016 Pain serves as a signal to elicit care from others. In turn, displaying pain might be attractive because of the benefits it might bring. Additionally, displaying pain is easy, because helpers distinguish poorly between genuine pain and faked pain. Hence,
Leander Steinkopf
doaj +1 more source
Frontiers in Pain Research, 2022 Music interventions accommodate the profound need for non-pharmacological pain treatment. The analgesic effect of listening to music has been widely demonstrated across studies. Yet, the specific mechanisms of action have still to be elucidated. Although
Sigrid Juhl Lunde +8 more
doaj +1 more source
Single-stage, three-arm, adaptive test strategies for non-inferiority trials with an unstable reference [PDF]
, 2021 For indications where only unstable reference treatments are available and use of placebo is ethically justified, three-arm `gold standard' designs with an experimental, reference and placebo arm are recommended for non-inferiority trials. In such designs, the demonstration of efficacy of the reference or experimental treatment is a requirement.
arxiv +1 more source
Causal progress with imperfect placebo treatments and outcomes [PDF]
arXiv, 2023 In the quest to make defensible causal claims from observational data, it is sometimes possible to leverage information from "placebo treatments" and "placebo outcomes". Existing approaches employing such information focus largely on point identification and assume (i) "perfect placebos", meaning placebo treatments have precisely zero effect on the ...
arxiv