Results 21 to 30 of about 504,627 (268)

Effects of placebos vs. SMS reminders on homework compliance in cognitive behavioral therapy for depression: a randomized trial

Mediterranean Journal of Clinical Psychology, 2022
Background: Nonadherence to homework assignments is a frequent problem among patients with depression during cognitive-behavioral therapy (CBT). The present study investigated the effects of two additional treatment components of CBT: a placebo and SMS ...
Nina Jurinec, Anne Schienle
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

An update on non-pharmacological interventions for pain relief

Cell Reports Medicine
Summary: Chronic pain affects a substantial portion of the population, yet current treatments often fail to provide adequate relief. Non-pharmacological interventions, which target behaviors and brain processes underlying the experience of pain, hold ...
Yang Wang, Rachel Aaron, Nadine Attal, Luana Colloca   +3 more
doaj   +1 more source

Error-related negativity and the misattribution of state-anxiety following errors: On the reproducibility of Inzlicht and Al-Khindi (2012)

Frontiers in Human Neuroscience, 2016
In their innovative study, Inzlicht and Al-Khindi (2012) demonstrated that participants who were allowed to misattribute their arousal and negative affect induced by errors to a placebo beverage had a reduced error-related negativity (ERN/Ne) compared to
Carmen Cano Rodilla, André Beauducel, Anja Leue   +2 more
doaj   +1 more source

Placebo Responses and Placebo Effects in Functional Gastrointestinal Disorders

Frontiers in Psychiatry, 2020
Much has been written about the placebo effects in functional gastrointestinal disorders (FGD), especially in irritable bowel syndrome (IBS), driven by the early hypothesis that in randomized controlled trials (RCTs) of IBS, the placebo effect might be ...
Paul Enck, Sibylle Klosterhalfen
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Efficacy of Cheiranthus Cheiri in the Treatment of Pericoronitis: A Double-blind, Randomized, Placebo-controlled Trial with Molecular Docking

Dentistry and Medical Research
Context: Pericoronitis is the soft-tissue inflammation surrounding the dental crown in a semi-erupted lower third molar. Patients with early-stage pericoronitis experience discomfort, redness, swelling, mucosal ulceration, and loss of function.
Shubhamoy Ghosh, Aritra Roy Chowdhury, Sarbendu Paul, Avipsha Sarkar, Abhijit Rana, Mousumi Koley, Indrani Halder, Suman Chandra, Subhranil Saha   +8 more
doaj   +1 more source

Study of the placebo effect with a placebo test

Comprehensive Psychiatry, 1968
Summary This paper briefly reviewed several methodological problems in studies of the placebo effect. The importance of finding appropriate measures of placebo effect was emphasized. This led to an attempt to develop a more valid and reliable test of placebo reactivity.
A K, Shapiro, H, Wilensky, E L, Struening   +2 more
openaire   +2 more sources

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Development and Psychometric Evaluation of the Hope in Medicine Scale

Clinical Psychology in Europe
[Background] Hope is an integral, multi-dimensional part of seeking medical treatment. The aim of this study was to develop a self-report scale, the Hope in Medicine (HIM) scale, to measure different modes of hoping in relation to the course of symptoms,
Lea Balthasar, Anne-Kathrin Bräscher, Ted J. Kaptchuk, Sarah K. Ballou, Tobias Kube   +4 more
doaj   +1 more source