Results 21 to 30 of about 748,749 (317)

Placebo and Nocebo: What are the reasons why each individual reacts differently [PDF]

, 2022
openL'obiettivo della tesi è quello di individuare, se esistono, le motivazioni ed i fattori che sono coinvolti nel verificarsi dell'effetto placebo e dell'effetto nocebo.
FORESTI, FEDERICA
core  

Placebo effects on the neurologic pain signature: A meta-analysis of individual participant functional magnetic resonance imaging data

, 2018
Importance Placebo effects reduce pain and contribute to clinical analgesia, but after decades of research, it remains unclear whether placebo treatments mainly affect nociceptive processes or other processes associated with pain evaluation.Objective We ...
Leknes, S., Schenk, L., Benedetti, F., Zunhammer, M., Choi, J., Büchel, C., Kaptchuk, T., Müllner-Huber, A., Wager, T., Kong, J., Wrobel, N., Ellingsen, D., Kirsch, I., Lamm, C., Lui, F., Schmid, J., Theysohn, N., Colloca, L., Tracey, I., Porro, C., Zeidan, F., Duzzi, D., Gollub, R., Kessner, S., Rütgen, M., Eippert, F. ; https://orcid.org/, Bingel, U., Elsenbruch, S., Geuter, S., Atlas, L.   +29 more
core   +1 more source

Developing a placebo-controlled trial in surgery: issues of design, acceptability and feasibility [PDF]

, 2011
<p>Background: Surgical placebos are controversial. This in-depth study explored the design, acceptability, and feasibility issues relevant to designing a surgical placebo-controlled trial for the evaluation of the clinical and cost effectiveness ...
Campbell, MK, McDonald, AM, Skea, Z.C, Sutherland, AG, ZC Skea, Norrie, J.D, Campbell, M.K., Cuthbertson BH, Bridgman, S., McDonald, A.M, BH Cuthbertson, AM McDonald, McDonald AM, RV Carlson, McDonald, A.M., Skea, Z.C., S Bridgman, Carlson, R V, Entwistle, V.A, Sutherland, A.G, Cuthbertson, B H, JD Norrie, Norrie, J. D., Campbell, M K, Cuthbertson, B. H., Skea, Z. C., Skea, ZC, Carlson, RV, Sutherland AG, null null, MK Campbell, Carlson, R.V., Entwistle, Vikki, McDonald, A M, Norrie, JD, Skea ZC, VA Entwistle, Carlson, R.V, Skea, Z C, AG Sutherland, Entwistle, V A, Carlson RV, Entwistle, V.A., Norrie, J D, Sutherland, A.G., Bridgman, S, Norrie, J.D., Entwistle, V. A., Sutherland, A G, Campbell, M.K, Entwistle VA, McDonald, A. M., KORAL study group, Cuthbertson, B.H., Sutherland, A. G., Cuthbertson, B.H, Campbell MK, Campbell, M. K., Entwistle, VA, Cuthbertson, BH, Bridgman S, Carlson, R. V., Norrie JD   +62 more
core   +2 more sources

Lack of Effects of the Presence of a Dog on Pain Perception in Healthy Participants—A Randomized Controlled Trial

Frontiers in Pain Research, 2021
Animal-assisted interventions (AAIs) have been shown to be effective in the treatment of pain. Studies suggest that relationships with animals can have comparable qualities to relationships with humans and that this enables animals to provide social ...
Cora Wagner, Jens Gaab, Cosima Locher, Cosima Locher, Cosima Locher, Karin Hediger, Karin Hediger, Karin Hediger, Karin Hediger   +8 more
doaj   +1 more source

Efficacy of modern antipsychotics in placebo-controlled trials in bipolar depression: a meta-analysis – results to be interpreted with caution [PDF]

, 2010
Randomized, controlled trials have demonstrated efficacy for second-generation antipsychotics in the treatment of acute mania in bipolar disorder. Despite depression being considered the hallmark of bipolar disorder, there are no published systematic ...
Goikolea, José Manuel, Krishnadas, R., Vieta i Pascual, Eduard, 1963-, Valentí Ribas, Marc, Sánchez-Moreno, José, Torres, Ferran, Livingston, M., Cruz, Nuria   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Placebo Effect in the Treatment of Depression and Anxiety

Frontiers in Psychiatry, 2019
The aim of this review is to evaluate the placebo effect in the treatment of anxiety and depression. Antidepressants are supposed to work by fixing a chemical imbalance, specifically, a lack of serotonin or norepinephrine in the brain.
Irving Kirsch
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Placebo and Non-specific Effects in Reconsolidation-Based Treatment for Arachnophobia

Frontiers in Psychiatry, 2021
The idea that maladaptive memories may be rendered susceptible to interference after reactivation raises the possibility of reactivating and neutralizing clinically-relevant emotional memories.
James W. B. Elsey, Merel Kindt
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source