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Placebos: A Review of The Placebo Response

American Journal of Gastroenterology, 2000
Placebos have been a component of healing since the beginning. Whether consciously or unconsciously given, they are largely responsible for the success of medicine before randomized trials. Yet, even in this era of "evidence-based medicine," placebos remain enigmatic, and elicit mixed attitudes from divers disciplines.
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The placebo effect

European Journal of Nuclear Medicine and Molecular Imaging, 1997
The placebo effect will have a growing importance in the field of nuclear medicine as the potentials for palliative therapy with internal sources are realized. It is important for nuclear medicine physicians and their colleagues to be familiar with the role of placebo responses in clinical trials, especially when such trials involve the subjective ...
M J, Heeg, K F, Deutsch, E, Deutsch
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Placebos and Metaphors

Perspectives in Biology and Medicine, 2023
ABSTRACT: The objective of this essay is to develop the argument that placebos are a species of metaphor and to demonstrate that an analysis of the figurative trope can help us elucidate the power of the placebo response. The cognitive and embodied responses to both metaphors and placebos stem from the transfer of meaning between two domains, each with
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Psychobiological Mechanisms of Placebo and Nocebo Effects: Pathways to Improve Treatments and Reduce Side Effects.

Annual Review of Psychology, 2019
Placebo effects constitute a major part of treatment success in medical interventions. The nocebo effect also has a major impact, as it accounts for a significant proportion of the reported side effects for many treatments.
K. Petrie, W. Rief
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Placebos and the Placebo Effect in Drug Trials

2019
In this review, we explored different ways of controlling the placebo effects in clinical trials and described various factors that may increase/decrease the placebo effect in randomized placebo-controlled trials. These factors can be subdivided into four groups, and while not all factors are effective in every study and under all clinical conditions ...
Paul, Enck, Sibylle, Klosterhalfen
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Placebo et effet placebo

Annales Pharmaceutiques Françaises, 2005
Resume Le mot placebo est apparu pour la premiere fois dans un dictionnaire medical anglais en 1785. En France, il faudra attendre 1958 ! Ce terme designe a la fois un outil experimental permettant, par comparaison, l’evaluation rigoureuse de l’effet specifique d’un traitement et un effet non specifique inherent a toute therapeutique. Recemment remis
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The Placebo Response

Journal of Mental Science, 1956
In recent controlled trials, conducted by the authors (1956), we were interested to note the proportion of patients improving with the administration of placebos. A placebo is defined in the Shorter Oxford Dictionary (1944) as “A medicine given more to please than to benefit the patient”.
R W, TIBBETTS, J R, HAWKINGS
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The concept of placebo

Science and Engineering Ethics, 2004
This paper attempts to define the concept of placebo as it is used in the clinical context The author claims that X is a placebo if and only if X has such a property dp, that whenever in a therapeutic situation T a stimulus S appears, then in attending conditions A, it will cause a beneficial reaction R in the patient.
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Placebo analgesia

Neurological Sciences, 2006
The placebo effect is the effect that follows the administration of an inert treatment (the placebo), be it pharmacological or not. It is important to understand that a placebo procedure simulates a therapy through the surrounding psychosocial context.
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The Placebo Effect

JAMA: The Journal of the American Medical Association, 1985
To the Editor.— Drs Kramer and Shapiro 1 give some valuable guidelines to improving the quality of research in their article, "Scientific Challenges in the Application of Randomized Trials," in the Nov 16, 1984, issue ofThe Journal. However, I'm afraid they perpetuate some of the misunderstandings concerning the nature of the placebo effect and its ...
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