Results 361 to 370 of about 1,501,016 (387)
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Phase III Randomized Trial of Ipilimumab Plus Etoposide and Platinum Versus Placebo Plus Etoposide and Platinum in Extensive-Stage Small-Cell Lung Cancer.

Journal of Clinical Oncology, 2016
Purpose Patients with extensive-stage disease small-cell lung cancer (SCLC) have poor survival outcomes despite first-line chemotherapy with etoposide and platinum.
M. Reck   +19 more
semanticscholar   +1 more source

Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks.

Arthritis & Rheumatism, 2006
OBJECTIVE To determine the efficacy and safety of treatment with rituximab plus methotrexate (MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response to anti-tumor necrosis factor (anti-TNF) therapies and to explore the ...
S. Cohen   +12 more
semanticscholar   +1 more source

Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil.

Journal of Clinical Oncology, 2009
PURPOSE Bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor, improves survival when combined with carboplatin/paclitaxel for advanced nonsquamous non-small-cell lung cancer (NSCLC). This randomized phase III trial investigated
M. Reck   +10 more
semanticscholar   +1 more source

The placebo effect

European Journal of Nuclear Medicine and Molecular Imaging, 1997
The placebo effect will have a growing importance in the field of nuclear medicine as the potentials for palliative therapy with internal sources are realized. It is important for nuclear medicine physicians and their colleagues to be familiar with the role of placebo responses in clinical trials, especially when such trials involve the subjective ...
Mary Jane Heeg   +2 more
openaire   +2 more sources

Placebos and the Placebo Effect in Drug Trials

2019
In this review, we explored different ways of controlling the placebo effects in clinical trials and described various factors that may increase/decrease the placebo effect in randomized placebo-controlled trials. These factors can be subdivided into four groups, and while not all factors are effective in every study and under all clinical conditions ...
Sibylle Klosterhalfen, Paul Enck
openaire   +3 more sources

The Placebo Response

Journal of Mental Science, 1956
In recent controlled trials, conducted by the authors (1956), we were interested to note the proportion of patients improving with the administration of placebos. A placebo is defined in the Shorter Oxford Dictionary (1944) as “A medicine given more to please than to benefit the patient”.
R W Tibbetts, J R Hawkings
openaire   +3 more sources

Placebo Effects Without Placebos? More Reason to Abandon the Paradoxical Placebo

The American Journal of Bioethics, 2009
When Miller and Colloca (2009) say that, “The placebo effect is a real neurobiological phenomenon” (4), they imply that placebos can be distinguished from non-placebos at some fundamental level.
openaire   +3 more sources

The placebo effect

Journal of Allergy and Clinical Immunology, 1986
Historically the term placebo harks back to the 116th psalm in the Hebrew bible. The ninth verse of this psalm begins with the word “et-ha-lech” (I shall walk), which was strangely translated into the Septuagint Greek as “euarestiso” and then into its Vulgate Latin equivalent of “placebo,” the first-person singular future tense of the verb meaning to ...
openaire   +3 more sources

Panacea or Placebo?

Archives of Internal Medicine, 1979
To the Editor.— The editorial by Dr Richard W. Welch, in theArchives(138:1208-1209, 1978), very appropriately indicated the narrow spectrum of proved clinical usefulness of cimetidine. Without any intention of detracting from this editorial opinion, I would suggest that under certain circumstances there may be other very narrow indications for the ...
openaire   +3 more sources

Flunarizine in Prophylaxis of Childhood Migraine: A Double-Blind, Placebo-Controlled, Crossover Study

Cephalalgia, 1988
F. Sorge   +5 more
semanticscholar   +1 more source

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