Results 171 to 180 of about 935,031 (288)

Transcranial electric stimulation in chronic pain: Effects on quality of life, physical function, activity and clinical status

Journal of Neuropsychology, EarlyView.
Abstract Transcranial electric stimulation represents a promising non‐invasive neuromodulatory technique targeting maladaptive nociplastic changes in chronic pain (CP) with analgesic effects. However, its impact beyond pain reduction on broader outcomes such as quality of life (QoL) and physical function remains unclear.
Antonio Gil‐Ugidos, María López‐Corchón, Gavriella Τsiarleston, Víctor Segura‐Jiménez, María Teresa Carrillo‐de‐la‐Peña   +4 more
wiley   +1 more source

Biofeedback‐Based Therapy in Patients With Myofascial Orofacial Pain and Bruxism: An Umbrella Review

Journal of Oral Rehabilitation, EarlyView.
This umbrella review of 11 systematic reviews found that biofeedback may reduce masticatory muscle activity, but its effects on myofascial orofacial pain and bruxism remain uncertain. Methodological limitations, heterogeneous protocols, and predominantly low‐quality evidence underscore the need for rigorous, standardized clinical trials.
Celine Beriger, Kathrin Kohout, Aleksandra Zumbrunn, Edwin Ruales‐Carrera, Tan Fırat Eyüboğlu, Mutlu Özcan   +5 more
wiley   +1 more source

The Impact of Injury Severity, Sex, and Nociceptor Activity on Post‐Traumatic Temporomandibular Joint Osteoarthritis in Mice

Journal of Oral Rehabilitation, EarlyView.
Repeated TMJ injury in mice demonstrated that greater injury severity and female sex exacerbate post‐traumatic TMJ degeneration. While short‐term nociceptor inhibition reduced pain without affecting degeneration, prolonged inhibition modestly attenuated degeneration, suggesting that persistent post‐traumatic pain contributes to TMJ osteoarthritis ...
Ishraq Alshanqiti, Jiaxin Hu, Swarnalakshmi Raman, Ghazaal Parastooei, Man‐Kyo Chung   +4 more
wiley   +1 more source

Full‐Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) Improves Symptoms of Rett Syndrome: An Open‐Label Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating, Y. Ogru, T. G. Duthy, L. Douglas, K. Lichkus, E. Isikgel, M. C. Fahey, C. Ellaway   +7 more
wiley   +1 more source

APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy

Journal of Pain Research, 2019
Eugene R Viscusi,1 Franck Skobieranda,2 David G Soergel,2 Emily Cook,2 David A Burt,2 Neil Singla3 1Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA; 2Trevena Inc., Chesterbrook, PA, USA ...
Viscusi ER, Skobieranda F, Soergel DG, Cook E, Burt DA, Singla N   +5 more
doaj  

Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley   +1 more source

Aseptic meningitis due to intravenous immunoglobulin therapy (IVIG) in therapy‐refractory pyoderma gangraenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber, Knut Schäkel, Alexander Enk, Julia K. Winkler   +3 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Sex Differences in the Blood Oxygen Level-Dependent Signal to Placebo Analgesia and Nocebo Hyperalgesia in Experimental Pain: A Functional MRI Study. [PDF]

Front Behav Neurosci, 2021
Shi Y, Zhan H, Zeng Y, Huang S, Cai G, Yang J, Wu W.   +6 more
europepmc   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source