Results 291 to 300 of about 14,301,803 (394)

Why and how do we perform physical examination(s) in clinical trials? A use case of drug intervention trials in type 2 diabetes mellitus

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study was to determine the purpose and use of physical examination (PE) in phase 3 and 4 drug interventional clinical trials within type 2 diabetes mellitus. Methods A total of 226 clinical trial protocols identified from the ClinicalTrials.gov database were systematically reviewed by five researchers.
Julia Kopanz, Amy Rogers, Lina Pérez‐Breva, Emily Hall, Prashasthi Devaiah, Isla S. Mackenzie, Bart Lagerwaard, Diederick E. Grobbee, Mira G. P. Zuidgeest, on behalf of the Trials@Home consortium   +9 more
wiley   +1 more source

[Placebo effect in the treatment with antidepressants : Implications for the scientific evaluation and clinical use of pharmaceutical treatments of depression]. [PDF]

Nervenarzt
Rief W, Kube T.
europepmc   +1 more source

Genetics and the placebo effect: the placebome.

Trends in Molecular Medicine, 2015
Kathryn T. Hall, J. Loscalzo, T. Kaptchuk   +2 more
semanticscholar   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

British Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl, Rod Hughes, Joachim Almquist, David Close, Jukka Mäenpää, Ulrika Tehler, Tina Jellesmark Jensen, Szilárd Nemes, Anne‐Kristina Mercier, Zala Jevnikar, Pablo Forte Soto, Dave Singh   +11 more
wiley   +1 more source

Effect of recolonisation with "interfering" alpha streptococci on recurrences of acute and secretory otitis media in children: randomised placebo controlled trial

, 2001
Kees-Peter de Roos
openalex   +2 more sources

The placebo effect: From concepts to genes

Neuroscience, 2015
B. Colagiuri, Lieven A. Schenk, Michael D. Kessler, Susan D Dorsey, L. Colloca, L. Colloca   +5 more
semanticscholar   +1 more source

Climate Risk and Tax Avoidance of Climate‐Sensitive Firms

Business Strategy and the Environment, EarlyView.
ABSTRACT This paper studies corporate tax behavior under increasing risks related to climate change. Using observations for China's listed firms in climate‐sensitive sectors from 2000 to 2020, our results highlight that tax avoidance has been employed to hedge climate change risks for climate‐sensitive firms, whereas we do not find climate risk‐induced
Hanmin Dong, Lin Zhang
wiley   +1 more source

Molecular classification of the placebo effect in nausea. [PDF]

PLoS One, 2020
Meissner K, Lutter D, von Toerne C, Haile A, Woods SC, Hoffmann V, Ohmayer U, Hauck SM, Tschoep MH.   +8 more
europepmc   +1 more source

The effect of rizatriptan, ergotamine, and their combination on human peripheral arteries: a double‐blind, placebo‐controlled, crossover study in normal subjects [PDF]

, 2002
Peer Tfelt‐Hansen, Kaj N. Seidelin, Michael Stepanavage, Christopher Lines   +3 more
openalex   +1 more source

Optimizing Peripheral Nerve Block Placement in Hip Surgery: A Cadaveric Study Mapping the Posterior Cutaneous Innervation

Clinical Anatomy, EarlyView.
ABSTRACT Optimizing analgesia after hip surgery enables more rapid recovery. However, peripheral nerve blocks (PNBs) often fail to provide adequate pain relief in the posterolateral hip as they typically target the lateral cutaneous nerve of the thigh (LCNT).
Ziki Gurney, Kenneth Saw Kai Wei, Leia Boote, Daniel Gareth Stolady, Benjamin Fox, Alan R. Norrish   +5 more
wiley   +1 more source