Results 101 to 110 of about 122,680 (303)

Placebo design in WHO-registered trials of Chinese herbal medicine need improvements

BMC Complementary and Alternative Medicine, 2019
Background Physical identical and pharmacological inert are the basic requirements for placebo design, which are essential in clinical trials to evaluate the efficacy of an intervention.
Xuan Zhang, Ran Tian, Chen Zhao, Xudong Tang, Aiping Lu, Zhaoxiang Bian   +5 more
doaj   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Placebos as a Source of Agency: Evidence and Implications

Frontiers in Psychiatry, 2019
Bioethical discussions surrounding the use of placebos in clinical practice have long revolved around the moral permissibility of deceiving a patient if it is likely to benefit them.
Phoebe Friesen
doaj   +1 more source

Evaluation of sixteen antimotion sickness drugs under controlled laboratory conditions [PDF]

Evaluation of antimotion sickness drugs under controlled laboratory ...
Graybiel, A., Wood, C. D.
core   +1 more source

Weiße Kittel, Schwarze Magie : Placebo nutzen, Nocebo kennen [PDF]

, 2013
Rezension zu: Magnus Heier, Andreas S. Ziegler: Weiße Kittel – Schwarze Magie. Placebos und Nocebos als Blendwerk der Medizin.
Hardy, Anne
core  

Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA) [PDF]

, 2013
Philip J. Mease, Roy Fleischmann, Atul Deodhar, J. Wollenhaupt, Majed Khraishi, D. Kielar, Franz Woltering, C. Stach, Bengt Hoepken, T. Arledge, Désirée van der Heijde   +10 more
openalex   +1 more source

Vitamin D3 and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial [PDF]

, 2022
Nyasha Dzavakwa, Molly Chisenga, Grace McHugh, Suzanne Filteau, Celia L. Gregson, Lackson Kasonka, Katharina Kranzer, Hildah Banda Mabuda, Hilda Mujuru, Nicol Redzo, Sarah Rowland‐Jones, Ulrich E. Schaible, Victoria Simms, Rashida A. Ferrand   +13 more
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Rehabilitation interventions for foot drop in neuromuscular disease [PDF]

, 2007
"Foot drop" or "Floppy foot drop" is the term commonly used to describe weakness or contracture of the muscles around the ankle joint.
Disler, Peter B., Sackley, Catherine, Turner-Stokes, Lynne, Wade, Derick T.   +3 more
core   +1 more source

A Placebo Controlled Crossover Trial of Liquid Fluoxetine on Repetitive Behaviors in Childhood and Adolescent Autism [PDF]

, 2004
Eric Hollander, Ann Phillips, William F. Chaplin, Karen Zagursky, Sherie Novotny, Stacey Wasserman, Rupa Iyengar   +6 more
openalex   +1 more source