Results 81 to 90 of about 22,441 (303)

What You Don’t Know Can Heal You: A Philosophical Inquiry into Placebos

Arụmarụka
This paper explores the role of placebos in healthcare, particularly within Complementary and Alternative Medicine (CAM) and African Traditional Medicine (ATM), to highlight both the challenges and potential benefits of their use.
Lerato MOTSOAHOLE
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

The Power of Placebo Interventions in Clinical Practice: A Cross-sectional Survey to Investigate the Perceptions and Utilization among Healthcare Professionals in the Western Region of Saudi Arabia

Journal of Nature and Science of Medicine
Background: Placebos and their effects are complex and varied processes, observed across a wide range of medical fields, potentially changing their perception and application in medicine and research.
Lin Mazen Jolha, Razan Adel Gobis, Basmala Abdulhalim Safour, Zainab Mohammed Awal Takroni, Waleed Khaled Daghmash, Aamina Shoaib Patel, Laila Mohammed Al Sankari, Abdulelah K. Alqawlaq, Nadeem Ikram   +8 more
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Analysis of the Choice of Control in Acupuncture Clinical Trials Involving Patients with Breast Cancer

Journal of Acupuncture Research
Control group selection in clinical trials is challenging, especially in acupuncture studies. A PubMed literature review of control groups in breast cancer acupuncture studies was performed and identified 67 studies for analysis.
Molly Siegel, Sylvia Baedorf Kassis, Weidong Lu, Im Hee Shin, Ting Bao, Barbara E. Bierer   +5 more
doaj   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

The ethics of placebos

South African Family Practice, 2013
The word “placebo”, first used during funeral ceremonies in the 14th century, is derived from old Latin and means “I shall please”. At the time, it was practice among Roman Catholics to hire professional mourners to wail vespers for the dead.
Donna Knapp van Bogaert, Gboyega A. Ogunbanjo   +1 more
doaj   +1 more source

PTBP1‐Mediated Alternative Splicing of DNAJB6 Promotes Everolimus Resistance in Clear Cell Renal Cell Carcinoma via EIF4B/PKIB/AKT/mTOR Positive Feedback Loop

Advanced Science, EarlyView.
PTBP1‐mediated alternative splicing drives a pathogenic switch to the DNAJB6b isoform in everolimus‐resistant clear cell renal cell carcinoma. This splicing event programs a positive feedback loop including EIF4B/PKIB/AKT/mTOR, promoting aggressive therapy resistance.
Xiu‐wu Pan, Hong‐feng Zheng, Mu‐chen Li, Jia‐lin Zhou, Hang‐biao Zhang, Dong‐hao Lyu, Yi‐fan Tang, Tian‐yue Yang, Yi‐fan Liu, Zi‐chang Liu, Wen‐jie Ma, Yuan‐bo Zong, Jian‐gui Liu, Zi‐xuan Gong, Hao Zhang, Ke‐qin Dong, Wang Zhou, Jian‐qin Ye, Xin‐gang Cui   +18 more
wiley   +1 more source

Open-label placebos reduce weight in obesity: a randomized controlled trial

Scientific Reports
Obesity is a major public health problem worldwide. Different approaches are known to face this problem, for example, dieting, surgery, or drug interventions. It has also been shown that placebos may help to reduce weight and hunger feelings, but the use
Michael Schaefer, Anja Kühnel, Sören Enge   +2 more
doaj   +1 more source

Use of placebo interventions among Swiss primary care providers

BMC Health Services Research, 2009
Background Placebo interventions can have meaningful effects for patients. However, little is known about the circumstances of their use in clinical practice.
Rosemann Thomas, Gnädinger Markus, Fässler Margrit, Biller-Andorno Nikola   +3 more
doaj   +1 more source