Results 151 to 160 of about 484,364 (380)
Objective Spinal cord (SC) atrophy correlates with and predicts the underlying progressive biology in active and non‐active multiple sclerosis (MS), thereby providing a biomarker for clinical trials and patient management. Initiation of disease‐modifying therapy (DMT) may be followed by early pronounced central nervous system (CNS) volume loss due to ...
Simone Sacco+26 more
wiley +1 more source
Placebos in the Treatment of Rheumatoid Arthritis and other Rheumatic Conditions
Eugene F. Traut, E Passarelli
openalex +1 more source
Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam+29 more
wiley +1 more source
The Meaning of Patent Citations: Report on the NBER/Case-Western Reserve Survey of Patentees [PDF]
A survey of recent patentees was conducted to elicit their perceptions regarding the importance of their inventions, the extent of their communication with other inventors, and the relationship of both importance and communication to observed patent ...
Adam B. Jaffe+2 more
core
RESPONSES TO ANALGESICS AND PLACEBO—STATISTICAL ANALYSIS
H.H. Keasling, E Gross
openalex +1 more source
Comparison of two doses of cimetidine and placebo in the treatment of duodenal ulcer: a multicentre trial. [PDF]
Karna Dev Bardhan+21 more
openalex +1 more source
Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis
Objective A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease ...
Ali Manouchehrinia+24 more
wiley +1 more source
OBJECTIVES/GOALS: Platform trials gain efficiency by sharing placebo controls among different study arms. However, the varying routes of administration make it unclear whether participants exposed to different placebos have similar outcomes.
Yue Gao+3 more
doaj +1 more source
Methotrexate compared with placebo in lung cancer [PDF]
Oleg S. Selawry+9 more
openalex +1 more source