Results 171 to 180 of about 122,680 (303)

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Clinical effect of intratympanic dexamethasone injection in acute unilateral tinnitus: A prospective, placebo‐controlled, multicenter study

, 2017
Hyun‐Jin Lee, Min‐Beom Kim, Shin‐Young Yoo, Shi Nae Park, Eui‐Cheol Nam, In Seok Moon, Ho‐Ki Lee   +6 more
openalex   +2 more sources

Efficacy and safety of ginger in osteoarthritis patients: a systematic review and meta-analysis of randomized placebo-controlled trials [PDF]

, 2014
Else Marie Bartels, Vanderlei Folmer, Henning Bliddal, Roy D. Altman, Carsten Bogh Juhl, Simon Tarp, Weiya Zhang, Robin Christensen   +7 more
openalex   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Talking placebo: a qualitative study of patients' attitudes toward open-label placebo implementation into clinical practice. [PDF]

Front Psychol
Frey Nascimento A, Bakis B, Gaab J, Schneider T, Papadopoulou A, Ritter M, Bernstein MH, Blease CR, Locher C.   +8 more
europepmc   +1 more source

Homeopathy and placebo - Synonym, similar or different? [PDF]

, 2007
Meissner, Karin, Zimmermann-Viehoff, Frank   +1 more
core   +1 more source

Effects of the Chinese herbal formula San-Huang Gu-Ben Zhi-Ke treatment on Stable Chronic Obstructive Pulmonary disease:study protocol of a randomized, double-blind, placebo-controlled trial [PDF]

, 2019
Yaqi Zu, Demin Li, Lei Xiang, Hongchun Zhang   +3 more
openalex   +1 more source

Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large‐Scale, Multi‐Cohort Proteomic Study

Annals of Neurology, EarlyView.
Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai, Joanne Wuu, Magdalena Koziczak‐Holbro, Andrea Malaspina, Volkan Granit, Jessica P. Hernandez, Anne Cooley, Ruchika Sachdev, Lili Yu, Michael Bidinosti, Ludivine Flotte, Mark Nash, Lori L. Jennings, James D. Berry, Lucie I. Bruijn, Sophie Brachat, Michael Benatar   +16 more
wiley   +1 more source

The Efficacy of Aromatherapy on Pain and Anxiety During Needle-Related Procedures in Adults: A Systematic Review and Meta-Analysis [Letter]. [PDF]

J Pain Res
Wang Z, Ke S, Liu Q.
europepmc   +1 more source

Intranasal Seletracetam in a Patient with Reading Epilepsy: First‐in‐Human Use to Prevent Reflex Seizures

Annals of Neurology, EarlyView.
We report the first human use of intranasal seletracetam (SEL) to prevent reflex seizures. A patient with epilepsy with reading‐induced seizures on levetiracetam (3,000 mg/day) continued to experience reading‐induced focal seizures with preserved consciousness.
Matthias J. Koepp, Kai‐Nicolas Poppert, Thomas Felder, Aljoscha Thomschewski, Sandra Lafenthaler, Pavel Klein, Alexander Rotenberg, Wolfgang Löscher, Chris Rundfeldt, Eugen Trinka   +9 more
wiley   +1 more source