Results 171 to 180 of about 116,751 (358)
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle+13 more
wiley +1 more source
Methotrexate compared with placebo in lung cancer [PDF]
Oleg S. Selawry+9 more
openalex +1 more source
Aims Daily broad‐spectrum micronutrients are being used by the general public and formulations are receiving research interest in mental health settings. Despite concerns about combining medicines and broad‐spectrum micronutrients in mental health care, there have not been any formal evaluations of potential interactions.
Bess M. Kew+7 more
wiley +1 more source
Double-blind comparison of tolamolol, propranolol, practolol, and placebo in the treatment of angina pectoris. [PDF]
Graham Jackson, L Atkinson, S. Oram
openalex +1 more source
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia+4 more
wiley +1 more source
Evaluation of sixteen antimotion sickness drugs under controlled laboratory conditions [PDF]
Evaluation of antimotion sickness drugs under controlled laboratory ...
Graybiel, A., Wood, C. D.
core +1 more source
Problems in deceptive medical procedures: an ethical and legal analysis of the administration of placebos [PDF]
Beth A. Simmons
openalex +1 more source