Results 181 to 190 of about 484,364 (380)

Maintenance of Remission After Tocilizumab Withdrawal in Patients With Glucocorticoid‐Dependent Polymyalgia Rheumatica

open access: yesArthritis &Rheumatology, EarlyView.
Objective The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) treatment in patients with glucocorticoid (GC)‐dependent polymyalgia rheumatica (PMR). TCZ reduced GC dose and disease activity at week 24. This study aimed to assess relapse rates after stopping TCZ treatment in patients achieving remission at week 24.
Baptiste Chevet   +24 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

open access: yesArthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek   +7 more
wiley   +1 more source

The effect of Barberry Juice supplement on Prostaglandin E2 level caused by intense aerobic activity in active young girls

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2017
Background and Aim: Intense exercise can cause damages caused by oxidative stress and inflammation and, as a result, reduce exercise performance. The present study aimed at determining the effect of barberry juice supplement on the inflammation caused by
Babak Hooshmand Moghadam   +2 more
doaj  

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun   +19 more
wiley   +1 more source

Talking placebo: a qualitative study of patients' attitudes toward open-label placebo implementation into clinical practice. [PDF]

open access: yesFront Psychol
Frey Nascimento A   +8 more
europepmc   +1 more source

A Placebo-Controlled Double-Blind Crossover Investigation of the Side Effects Attributed to Oral Contraceptives

open access: bronze, 1971
Joseph W. Goldzieher   +4 more
openalex   +1 more source

Peripheral Blood Gene Expression Profiling and Prognostic Significance for the Course of Interstitial Lung Disease in Patients With Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective We used data from the placebo arm of the Safety and Efficacy of Nintedanib in Systemic Sclerosis (SENSCIS) trial to determine the prognostic/predictive significance of peripheral blood cell (PBC) transcript modules for the course of forced vital capacity (FVC) in patients with systemic sclerosis–associated interstitial lung disease (SSc‐ILD ...
Shervin Assassi   +6 more
wiley   +1 more source

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