Results 61 to 70 of about 488,286 (382)

Placebo by proxy

open access: yesBMJ, 2011
Clinicians’ and family members’ feelings and perceptions about a treatment may influence their judgments about its ...
David J. Grelotti, Ted J. Kaptchuk
openaire   +4 more sources

Change in Cognition Following Ischaemic Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline can occur following ischaemic stroke. How cognition changes over time and associations with cognitive change are poorly understood. This study aimed to explore these issues over 2 years following ischaemic stroke.
Wenci Yan   +8 more
wiley   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich   +10 more
wiley   +1 more source

Trafficking in Cure and Harm: Placebos, Nocebos and the Curative Imaginary

open access: yesDisability Studies Quarterly, 2018
This article tracks the traffic of placebos, nocebos and the effects or meaning-responses that they solicit in order to contribute to wide-ranging critiques of the curative imaginary.
Suze G. Berkhout, Ada S. Jaarsma
doaj   +1 more source

Prescribing Placebos [PDF]

open access: yes, 2018
The use of placebos in medicine is an area of ethical questioning, but we often do not consider the effect of placebos on daily life. One’s preconceptions on the outcomes of exercise physically affect health. Studies show being aware of the advantages of
Cupp, Kelsey
core   +1 more source

Prophylactic Management of Vestibular Migraine: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Vestibular migraine (VM) is a neurological disorder characterized by episodic vertigo in patients with migraine, contributing to substantial functional impairment. Although VM is relatively common, a consensus on effective prophylactic treatments is lacking.
Hussain Ali Almohammed   +11 more
wiley   +1 more source

HREC members\u27 personal values influence decision making in contentious cases [PDF]

open access: yes, 2017
This article identifies 14 contentious issues faced by Human Research Ethics Committees (HRECs). The authors argue that HREC members will respond variably to these issues based on their own fundamental values and worldview. In particular, we propose that
Brewer, Keagan   +4 more
core   +1 more source

Rush to Judgment: The STI-Treatment Trials and HIV in Sub-Saharan Africa

open access: yes, 2015
Introduction: The extraordinarily high incidence of HIV in sub-Saharan Africa led to the search for cofactor infections that could explain the high rates of transmission in the region.
Akobeng   +76 more
core   +2 more sources

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

open access: yesArthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen   +14 more
wiley   +1 more source

Improvements in Health‐Related Quality of Life with Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post‐hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, Accepted Article.
Background While treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL change.
Austin Barry   +16 more
wiley   +1 more source

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