Results 61 to 70 of about 495,708 (385)

The role of placebos in family medicine: Implications of evidence and ethics for general practitioners.

open access: yesAustralian Journal of General Practice, 2019
BACKGROUND Placebo use is prevalent in primary care. A wealth of discourse on the ethical use of placebos in clinical contexts invariably assumes that placebos oblige practitioners to peddle in deception.
Charlotte R Blease
semanticscholar   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Evidencing general acceptability of open-label placebo use for tackling overtreatment in primary care: a mixed methods study

open access: yesBMC Medicine, 2023
Background Overtreatment poses a challenge to healthcare systems due to harmful consequences of avoidable side-effects and costs. This study presents the first account for examining the feasibility of placebo use for reducing overtreatment in primary ...
E. M. Krockow   +4 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen   +11 more
wiley   +1 more source

Trafficking in Cure and Harm: Placebos, Nocebos and the Curative Imaginary

open access: yesDisability Studies Quarterly, 2018
This article tracks the traffic of placebos, nocebos and the effects or meaning-responses that they solicit in order to contribute to wide-ranging critiques of the curative imaginary.
Suze G. Berkhout, Ada S. Jaarsma
doaj   +1 more source

Deceptive and open-label placebo effects in experimentally induced guilt: a randomized controlled trial in healthy subjects

open access: yesScientific Reports, 2022
Placebos are known to yield significant effects in many conditions. We examined deceptive and open-label placebo effects on guilt, which is important for self-regulation and a symptom of mental disorders.
Dilan Sezer, Cosima Locher, Jens Gaab
doaj   +1 more source

Prescribing Placebos [PDF]

open access: yes, 2018
The use of placebos in medicine is an area of ethical questioning, but we often do not consider the effect of placebos on daily life. One’s preconceptions on the outcomes of exercise physically affect health. Studies show being aware of the advantages of
Cupp, Kelsey
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Are treatments more effective than placebos? A systematic review and meta-analysis.

open access: yesPLoS ONE, 2013
BackgroundPlacebos are widely used in clinical practice in spite of ethical restrictions. Whether such use is justified depends in part on the relative benefit of placebos compared to 'active' treatments. A direct test for differences between placebo and
Jeremy Howick   +8 more
doaj   +1 more source

Clinical efficacy of probiotic mouthwash in the treatment of gingivitis patients in Himachal population

open access: yesJournal of International Clinical Dental Research Organization, 2017
This study was conducted to analyze the changes in gingival health in patients treated with probiotic containing mouth rinse. Thirty volunteers between 20 and 35 years were randomly divided into two groups.
Vikas Jindal   +5 more
doaj   +1 more source

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