Results 31 to 40 of about 17,086 (201)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Placement Delivery Array for Cache-Aided MIMO Systems

CoRR
We consider a $(G,L,K,M,N)$ cache-aided multiple-input multiple-output (MIMO) network, where a server equipped with $L$ antennas and a library of $N$ equal-size files communicates with $K$ users, each equipped with $G$ antennas and a cache of size $M$ files, over a wireless interference channel.
Yifei Huang, Kai Wan 0001, Minquan Cheng, Jinyan Wang, Giuseppe Caire   +4 more
openaire   +2 more sources

On the Placement Delivery Array Design for Coded Caching Scheme in D2D Networks

CoRR, 2017
20 ...
Jinyu Wang, Minquan Cheng, Qifa Yan, Xiaohu Tang 0004   +3 more
openaire   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane, Salama Makni, Mourad Kchaou, Ahmed El Hajjaji   +3 more
wiley   +1 more source

Placement Delivery Array Design via Attention-Based Deep Neural Network

CoRR, 2018
A decentralized coded caching scheme has been proposed by Maddah-Ali and Niesen, and has been shown to alleviate the load of networks. Recently, placement delivery array (PDA) was proposed to characterize the coded caching scheme. In this paper, a neural architecture is first proposed to learn the construction of PDAs.
Zhengming Zhang 0001, Meng Hua, Chunguo Li, Yongming Huang 0001, Luxi Yang   +4 more
openaire   +2 more sources

Microstructure Reconstruction in Battery Electrodes Using Machine Learning Based on Low‐Voltage Focused Ion Beam–Scanning Electron Microscopy Tomography Images

Advanced Engineering Materials, EarlyView.
Low‐voltage FIB‐SEM tomography combined with a image preprocessing pipeline improves phase contrast and enables reliable machine‐learning segmentation of conductive networks in lithium‐ion battery electrodes. Structural descriptors are extracted from segmented images, done semimanually and automated, and compared.
Lisa Beran, Vincent Nebel, Dominik Perius, Kshitij Kumar, Yannis Heim, Laura Bies, Tobias Kraus   +6 more
wiley   +1 more source

The Patient Engaged Research Center's Sustainable Funding Framework: A Path Towards Sustainable Patient Engagement in Care and Research Within a Health System

Learning Health Systems
Background Despite growing acknowledgement that patient engagement (PE) in research, quality improvement, and clinical care is important, models showcasing how learning health systems (LHSs) can sustain long‐term PE across endeavors remain scant.
Paige Coyne, Leah Copeland, Dana Murphy, Ashley Redding, Christine C. Johnson, Karen E. Kippen, Sara Santarossa   +6 more
doaj   +1 more source