Results 1 to 10 of about 468,315 (359)

PETN-Induced Antioxidative Properties in Endothelial Cells as a Target for Secondary Prevention of Endothelial Dysfunction in Pregnancy

Frontiers in Physiology, 2022
The NO-donor Pentaerytrithyltetranitrate (PETN) has vasodilatative properties and direct protective effects on endothelial cells. We formerly demonstrated that PETN, given to pregnant women during the second and third trimester, influences endothelial ...
Veronika Teichert, Veronika Teichert, Silke Große, Anna Multhaup, Jasmin Müller, Ruby N. Gutierrez-Samudio, Diana M. Morales-Prieto, Tanja Groten   +7 more
doaj   +1 more source

Impact of tissue processing on microbiological colonization in the context of placentophagy

Scientific Reports, 2022
A mother’s postpartum ingestion of raw or processed placental tissue—referred to as human maternal placentophagy—is an emerging health trend observed in industrialized nations.
Sophia K. Johnson, Jana Pastuschek, Daniel C. Benyshek, Yvonne Heimann, Anne Möller, Jürgen Rödel, Jacob White, Janine Zöllkau, Tanja Groten   +8 more
doaj   +1 more source

Decreased Expression of Pulmonary Homeobox NKX2.1 and Surfactant Protein C in Developing Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE)

Journal of Developmental Biology, 2023
Receptors for advanced glycation end-products (RAGE) are multi-ligand cell surface receptors of the immunoglobin superfamily prominently expressed by lung epithelium.
Derek M. Clarke, Katrina L. Curtis, Ryan A. Wendt, Brendan M. Stapley, Evan T. Clark, Nathan Beckett, Kennedy M. Campbell, Juan A. Arroyo, Paul R. Reynolds   +8 more
doaj   +1 more source

RAGE signaling during tobacco smoke-induced lung inflammation and potential therapeutic utility of SAGEs

BMC Pulmonary Medicine, 2022
Background Smoke exposure culminates as a progressive lung complication involving airway inflammation and remodeling. While primary smoke poses the greatest risk, nearly half of the US population is also at risk due to exposure to secondhand smoke (SHS).
Kelsey M. Hirschi-Budge, Kary Y. F. Tsai, Katrina L. Curtis, Gregg S. Davis, Benjamin K. Theurer, Anica M. M. Kruyer, Kyle W. Homer, Ashley Chang, Pam M. Van Ry, Juan A. Arroyo, Paul R. Reynolds   +10 more
doaj   +1 more source

A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells

Cells, 2021
Impaired DNA damage responses are associated with several diseases, including pregnancy complications. Recent research identified an ATM-kinase dependent function for the nuclear isoform of the receptor for advanced glycation end-products (RAGE) during ...
Kary Y.F. Tsai, Benton Tullis, Katrina L. Breithaupt, Rylan Fowers, Nelson Jones, Samuel Grajeda, Paul R. Reynolds, Juan A. Arroyo   +7 more
doaj   +1 more source

Lung Inflammation Is Associated with Preeclampsia Development in the Rat

Cells, 2022
Preeclampsia (PE) is an obstetric complication associated with significant health implications for the fetus and mother. Studies have shown a correlation between lung disease development and PE.
Katrina Curtis, Derek Clarke, Makayla Hanegan, Brendan Stapley, Ryan Wendt, Nathan Beckett, Cade Litchfield, Kennedy Campbell, Paul Reynolds, Juan Arroyo   +9 more
doaj   +1 more source

Beyond Uterine Natural Killer Cell Numbers in Unexplained Recurrent Pregnancy Loss: Combined Analysis of CD45, CD56, CD16, CD57, and CD138

Diagnostics, 2020
Changes in the number and cytotoxic potential of uterine Natural Killer (uNK) cells have been associated with reduced fertility. To provide a better characterization of immunophenotypes in the endometrium of women with uRPL (unexplained recurrent ...
Maia Chiokadze, Christin Bär, Jana Pastuschek, Boris V. Dons’koi, Kseniia G. Khazhylenko, Ekkehard Schleußner, Udo R. Markert, Rodolfo R. Favaro   +7 more
doaj   +1 more source

Identification of altered miRNAs and their targets in placenta accreta

Frontiers in Endocrinology, 2023
Placenta accreta spectrum (PAS) is one of the major causes of maternal morbidity and mortality worldwide with increasing incidence. PAS refers to a group of pathological conditions ranging from the abnormal attachment of the placenta to the uterus wall ...
José M. Murrieta-Coxca, Emanuel Barth, Emanuel Barth, Paulina Fuentes-Zacarias, Ruby N. Gutiérrez-Samudio, Tanja Groten, Alexandra Gellhaus, Angela Köninger, Angela Köninger, Manja Marz, Manja Marz, Udo R. Markert, Diana M. Morales-Prieto   +12 more
doaj   +1 more source

Paraoxonase 2 protein is spatially expressed in the human placenta and selectively reduced in labour [PDF]

, 2014
Humans parturition involves interaction of hormonal, neurological, mechanical stretch and inflammatory pathways and the placenta plays a crucial role.
A Abdulsid, A Abdulsid, A Abdulsid, A Many, Akrem Abdulsid, Ana Claudia Zenclussen, C Burdon, CJ Ng, CL Elliott, DA Stoltz, DI Draganov, DI Draganov, F Petraglia, Fiona Lyall, H-H Peng, HS Brar, I Witte, JF Teiber, JM McCord, JRG Challis, Kevin Hanretty, KJ Lee, M Shiner, R Lim, RS Dwarakanath, S Horke, Samy Alwarfaly, SL Primo-Parma, T Cindrova-Davies, U Borell, V Sitras, VC Allport, Y Xu   +32 more
core   +11 more sources

A case report of placenta fenestrate [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2021
Introduction: One of the variants of the placenta is the placenta fenestrate. In rare cases, the central part of the placental disc is missing. In some cases, there is a real hole in the placenta.
Firouze Ziaee, Fatemeh Zahra karimi, Masoumeh Mirteimouri, Elaheh Mansouri Ghezel Hesari   +3 more
doaj   +1 more source