Results 11 to 20 of about 334,165 (266)
High Altitude Medicine & Biology, 2012 Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, hypertension, metabolic changes, oxidative stress, mitochondrial dysfunction, and endoplasmic reticular stress.
Tissot van Patot, Martha C +3 more
openaire +4 more sources
Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells
STAR Protocols, 2022 Summary: Human trophoblast stem cells (hTSCs) are useful for studying human placenta development and diseases, but primed human pluripotent stem cells (hPSCs) routinely cultured in most laboratories do not support hTSC derivation.
Yanxing Wei +8 more
doaj +1 more source
The Scientific World Journal, 2013 Invasiveness of trophoblast and choriocarcinoma cells is in part mediated via leukemia inhibitory factor- (LIF-) induced activation of signal transducer and activator of transcription 3 (STAT3).
Diana M. Morales-Prieto +7 more
doaj +1 more source
Differential placental ceramide levels during gestational diabetes mellitus (GDM)
Reproductive Biology and Endocrinology, 2019 Background Gestational diabetes mellitus (GDM) is associated with important factors that influence fetal development. Sphingolipids are known to be associated with the development of diabetes.
Juan F. Mejia +8 more
doaj +1 more source
Reproductive Biology and Endocrinology, 2023 Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental functions, fetal development ...
Frantisek Staud +8 more
doaj +1 more source
C1431T Variant of PPARγ Is Associated with Preeclampsia in Pregnant Women
Life, 2021 Peroxisome proliferator-activated receptor γ (PPARγ) is essential for placental development, whose SNPs have shown increased susceptibility to pregnancy-related diseases, such as preeclampsia.
Fulin Liu +7 more
doaj +1 more source
Molecular Principles of Intrauterine Growth Restriction in Plasmodium Falciparum Infection
Frontiers in Endocrinology, 2019 Malaria in pregnancy still constitutes a particular medical challenge in tropical and subtropical regions. Of the five Plasmodium species that are pathogenic to humans, infection with Plasmodium falciparum leads to fulminant progression of the disease ...
Johanna Seitz +5 more
doaj +1 more source
Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts
PPAR Research, 2020 Trophoblasts, as the cells that make up the main part of the placenta, undergo cell differentiation processes such as invasion, migration, and fusion.
Fulin Liu +6 more
doaj +1 more source
Generation of two RNF2 homozygous knockout human embryonic stem cell lines by CRISPR/Cas9 system
Stem Cell Research, 2020 Human RNF2 (RING1B) gene is a critical epigenetic modification factor for embryonic development, pluripotency and differentiation of embryonic stem cells (ESCs). To further gain insights into the role of RNF2 in cell fate decisions of human ESCs, here we
Yongli Shan +7 more
doaj +1 more source
Influence of placenta previa type on blood preparation
Zhongguo shuxue zazhi, 2022 Objective To explore the corresponding strategies of blood preparation for placenta previa operation in our hospital according to the situation of blood transfusion during and after operation. Methods Ninety pregnant women with placenta previa (complete,
Jia XIE +5 more
doaj +1 more source