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The chorioallantoic placenta is the defining organ of eutherians that has enabled prolonged intrauterine gestation. As such, normal placental development and function are essential for mammalian reproductive success. Reflecting the key role of this organ in providing nutrients to the embryo, the characteristic cell type that forms substantial parts of ...
Rosalind M. John +2 more
openaire +3 more sources
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu +9 more
wiley +1 more source
Chorioangioma of placenta is the commonest benign tumour of the placenta. It consists of a benign angioma arising from chorionic tissue. We report a case of placental chorioangioma which was diagnosed in the post partum period in a patient with polyhydramnios who went into preterm labor and delivered a premature baby. Keywords: chorioangioma ...
Gahana Gurung, Nilam Subedi, Rubby Das
openaire +4 more sources
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina +9 more
wiley +1 more source
Exposure to cigarette smoke is known to induce disease during pregnancy. Recent evidence showed that exposure to secondhand smoke (SHS) negatively impacts fetal and placental weights, leading to the development of intrauterine growth restriction (IUGR ...
Madison N. Kirkham +8 more
doaj +1 more source
The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as their precursor cholesterol are required for successful establishment and maintenance of pregnancy and proper development of the fetus.
Waranya Chatuphonprasert +3 more
doaj +1 more source
Comparing placentas from normal and abnormal pregnancies [PDF]
This report describes work carried out at a Mathematics-in-Medicine Study Group. It is believed that placenta shape villous network characteristics are strongly linked to the placenta’s efficiency, and hence to pregnancy outcome.
Cotter, SL +12 more
core
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
The role of Plasmodium falciparum var genes in malaria in pregnancy [PDF]
Sequestration of Plasmodium falciparum-infected erythrocytes in the placenta is responsible for many of the harmful effects of malaria during pregnancy. Sequestration occurs as a result of parasite adhesion molecules expressed on the surface of infected ...
Andrews +51 more
core +1 more source

