Results 71 to 80 of about 581,453 (310)

Multiple Choriangiomas of Placenta [PDF]

, 2011
Placental chorangiomas, not an uncommon condition is often small and hence usually goes unnoticed . However the incidence of complications is high when the chorangioma is large. We hereby present an unusual case of large and multiple choriangiomas with
Krishnan, Nalini, MG, Abhishek, MU, Thejaswini, S, Vijay Shankar, Shivakumar, Swarna   +4 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Antiphospholipid antibodies induce endothelial procoagulant activity and release of extracellular vesicles independently of a second hit

Frontiers in Immunology
IntroductionAntiphospholipid antibodies (aPLs) can promote thrombosis in vivo, but evidence from both animal models and clinical data suggests that they act as a ‘first hit’ and may require a ‘second hit’, typically an inflammatory stimulus, to induce ...
Daniel Álvarez, Daniel Álvarez, Daniel Álvarez, Hephzibah E. Winter, Udo R. Markert, Ángela P. Cadavid J., Ángela P. Cadavid J., Diana M. Morales-Prieto   +7 more
doaj   +1 more source

Early onset preeclampsia is characterized by altered placental lipid metabolism and a premature increase in circulating FABP4 [PDF]

, 2010
Preeclampsia is a pregnancy-associated disorder that manifests as a sudden increase in maternal blood pressure accompanied by proteinuria. Because the placenta is a key organ in preeclampsia, we used proteomic and lipidomic analyses to compare placentae ...
Aaron Booy, Delfina Siroen, Gilles Lajoie, Jennifer Ballard, Nicholas Carruthers, Victor H. Han   +5 more
core   +1 more source

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

The effect of maternal iron deficiency on zinc and copper levels and on genes of zinc and copper metabolism during pregnancy in the rat [PDF]

, 2019
Fe deficiency is relatively common in pregnancy and has both short- and long-term consequences. However, little is known about the effect on the metabolism of other micronutrients.
Cottin, Sarah C., Currie, Valerie J., Gambling, Lorraine, Hayes, Helen E., McArdle, Harry J., Roussel, Guenievre   +5 more
core   +5 more sources

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Ingested bovine amniotic fluid enhances morphine antinociception in rats [PDF]

, 2000
Ingestion by rats of rat placenta or amniotic fluid enhances opioid-mediated, or partly opioid-mediated, antinociception produced by morphine injection, vaginal or cervical stimulation, late pregnancy, and foot shock.
Corpening, James W., Doerr, Jean C., Kristal, Dr. Mark B.   +2 more
core   +1 more source

Phormosoma placenta subsp. placenta placenta Thomson 1872

, 2019
Phormosoma placenta placenta Thomson, 1872b Reports for the Azores: Phormosoma placenta Thomson, 1872 b— $ Mortensen 1927b: 25; Mortensen 1935: 125–135, figs. 80–82, pl. 1, figs. 1–5, pl. 2, figs. 1–19, pl. 74, figs. 1–6, 19; Marques 1980: 105; Benavides-Serrato et al. 2012: 53.
Madeira, Patrícia, Kroh, Andreas, Cordeiro, Ricardo, De, António M., Martins, Frias, Ávila, Sérgio P.   +5 more
openaire   +2 more sources

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source