Results 61 to 70 of about 558,488 (351)

Modelling the placenta from the bottom up: digital phenotyping of human placenta histology [PDF]

Accurate placenta histopathology assessment is essential for immediate and lifelong clinical management of mother and newborn health. However, the placenta’s heterogeneity and high disease tolerance are challenging for robust, reproducible histological ...
Vanea, Claudia
core   +1 more source

Changes in mitochondrial respiration in the human placenta over gestation [PDF]

, 2017
Introduction: Placental mitochondria are subjected to micro-environmental changes throughout gestation, in particular large variations in oxygen. How placental mitochondrial respiration adapts to changing oxygen concentrations remains unexplored ...
Christopher Hedges, Chamley, Lawrence W, Moran, Stephanie, Chamley, Lawrence W., Alvsaker, Anna, Perkins, Anthony V, Stephanie Moran, Hickey, Anthony JR, Lawrence W. Chamley, Holland, Olivia J, Holland, Olivia, Hedges, Christopher, Anna Alvsaker, Anthony V. Perkins, Perkins, Anthony, Hickey, Anthony, Olivia J. Holland, Anthony J.R. Hickey   +17 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

THE PLACENTA. [PDF]

The Lancet
n ...
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Comparing placentas from normal and abnormal pregnancies [PDF]

, 2010
This report describes work carried out at a Mathematics-in-Medicine Study Group. It is believed that placenta shape villous network characteristics are strongly linked to the placenta’s efficiency, and hence to pregnancy outcome.
Kritz, M., Stechi, A., Siggers, J., Preedy, Katharine, Klika, V., Cotter, SL, Gallimore, L., Greenhalgh, David, Kennedy, S., Whittaker, R., Pu, I., Nelson, P., Heazell, Alexander   +12 more
core   +4 more sources

Single cell transcriptional signatures of the human placenta in term and preterm parturition

bioRxiv, 2019
More than 135 million births occur each year; yet, the molecular underpinnings of human parturition in gestational tissues, and in particular the placenta, are still poorly understood. The placenta is a complex heterogeneous organ including cells of both
R. Pique-Regi, R. Romero, Adi L. Tarca, E. Sendler, Yi Xu, V. Garcia-Flores, Y. Leng, Francesca Luca, S. Hassan, N. Gomez‐Lopez   +9 more
semanticscholar   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Exploration on the relationship between hypoxia inducible factor-1α and morbidly adherent placenta

Clinical and Experimental Obstetrics & Gynecology, 2020
Objective: This study aims to explore the role of hypoxia inducible factor-1α (HIF-1α) in morbidly adherent placenta (MAP). Materials and Methods: Ten pregnant women with placenta increta, 20 pregnant women with placenta previa, and 30 normal pregnant ...
J.Y. Yan, P.P. Chen, L.L. Jiang, H.L. Zhang, Q. Han, R.X. Chen, Q.J. Zhang   +6 more
doaj   +1 more source

The importance of placenta donation for the use of the amniotic membrane: a literature review

, 2022
openBACKGROUND: La donazione di placenta per l’utilizzo della membrana amniotica a scopo di trapianto è un consenso ancora non sufficientemente diffuso.
MARTELLI, FEDERICA
core