Results 21 to 30 of about 725,003 (400)

PETN-Induced Antioxidative Properties in Endothelial Cells as a Target for Secondary Prevention of Endothelial Dysfunction in Pregnancy

open access: yesFrontiers in Physiology, 2022
The NO-donor Pentaerytrithyltetranitrate (PETN) has vasodilatative properties and direct protective effects on endothelial cells. We formerly demonstrated that PETN, given to pregnant women during the second and third trimester, influences endothelial ...
Veronika Teichert   +7 more
doaj   +1 more source

Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy.

open access: yesJournal of the American Chemical Society, 2023
Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nonviral platform for mRNA delivery. While they have been explored for applications including vaccines and gene editing, LNPs have not been investigated for placental insufficiency ...
K. Swingle   +12 more
semanticscholar   +1 more source

Impact of tissue processing on microbiological colonization in the context of placentophagy

open access: yesScientific Reports, 2022
A mother’s postpartum ingestion of raw or processed placental tissue—referred to as human maternal placentophagy—is an emerging health trend observed in industrialized nations.
Sophia K. Johnson   +8 more
doaj   +1 more source

Decreased Expression of Pulmonary Homeobox NKX2.1 and Surfactant Protein C in Developing Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE)

open access: yesJournal of Developmental Biology, 2023
Receptors for advanced glycation end-products (RAGE) are multi-ligand cell surface receptors of the immunoglobin superfamily prominently expressed by lung epithelium.
Derek M. Clarke   +8 more
doaj   +1 more source

RAGE signaling during tobacco smoke-induced lung inflammation and potential therapeutic utility of SAGEs

open access: yesBMC Pulmonary Medicine, 2022
Background Smoke exposure culminates as a progressive lung complication involving airway inflammation and remodeling. While primary smoke poses the greatest risk, nearly half of the US population is also at risk due to exposure to secondhand smoke (SHS).
Kelsey M. Hirschi-Budge   +10 more
doaj   +1 more source

Lung Inflammation Is Associated with Preeclampsia Development in the Rat

open access: yesCells, 2022
Preeclampsia (PE) is an obstetric complication associated with significant health implications for the fetus and mother. Studies have shown a correlation between lung disease development and PE.
Katrina Curtis   +9 more
doaj   +1 more source

The Hypoxic Placenta [PDF]

open access: yesHigh Altitude Medicine & Biology, 2012
Hypoxia of the placenta is integral to complications of pregnancy, including preeclampsia, intrauterine growth restriction, and small-for-gestational age babies. Hypoxia in the placenta is associated with vascular remodeling, hypertension, metabolic changes, oxidative stress, mitochondrial dysfunction, and endoplasmic reticular stress.
Martha C. Tissot van Patot   +4 more
openaire   +4 more sources

A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells

open access: yesCells, 2021
Impaired DNA damage responses are associated with several diseases, including pregnancy complications. Recent research identified an ATM-kinase dependent function for the nuclear isoform of the receptor for advanced glycation end-products (RAGE) during ...
Kary Y.F. Tsai   +7 more
doaj   +1 more source

The Pivotal Role of the Placenta in Normal and Pathological Pregnancies: A Focus on Preeclampsia, Fetal Growth Restriction, and Maternal Chronic Venous Disease

open access: yesCells, 2022
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ grows incredibly rapidly during this period, acting as a mastermind behind different fetal and maternal processes. The relevance of the placenta extends far beyond
M. Ortega   +11 more
semanticscholar   +1 more source

The placenta: a multifaceted, transient organ

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2015
Graham J Burton, Abigail Fowden
exaly   +2 more sources

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