Results 71 to 80 of about 232,069 (266)

A comparative study of human ovarian tissue xenotransplantation in two different strains of rats

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The study involved performing ovariectomy on female Hooded and Wistar rats 14 days prior to transplantation. Following ovariectomy, the rats received cyclosporine starting five days before surgery to suppress the immune response and prevent graft rejection.
Mohammad Ayoubipour   +5 more
wiley   +1 more source

A potential strategy for improving offspring behavior in maternal immune activation: Amantadine‐mediated suppression of neuroinflammation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Amantadine (AMA) regulates neurocyte apoptosis and inhibits neurocyte inflammation to prevent maternal immune activation (MIA) from affecting offspring behavior. Abstract Background Maternal viral infection during pregnancy can lead to maternal immune activation (MIA), increasing the risk of neurodevelopmental disorders in offspring.
Jianfei Wu   +8 more
wiley   +1 more source

Enhanced Exosome Production in Mesenchymal Stem Cells via Extracellular Matrix‐Incorporated 3D Spheroid Printing

open access: yesAdvanced NanoBiomed Research, EarlyView.
A novel extracellular matrix (ECM)‐integrated mesenchymal stem cell spheroid bioprinting technology has been introduced to significantly enhance exosome production for therapeutic applications. By optimizing spheroid size and ECM composition, the study demonstrates an 18.4‐fold increase in exosome yield compared to 2D culture systems.
Jun‐Ho Heo   +3 more
wiley   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

open access: yesHepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid   +20 more
wiley   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

open access: yesAdvanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos   +2 more
wiley   +1 more source

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