Results 41 to 50 of about 2,454,543 (303)

The ABCG2 efflux transporter from rabbit placenta: cloning and functional characterization [PDF]

, 2016
In human placenta, the ATP-binding cassette efflux transporter ABCG2 is highly expressed in syncytiotrophoblast cells and mediates cellular excretion of various drugs and toxins.
Müller, Marian, Ritz, Vera, Halwachs, Sandra, Kneuer, Carsten, Honscha, Walther, Gohlsch, Katrin   +5 more
core   +1 more source

IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

, 2013
Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve themed workshops, four of which are summarized in this report.
Kikuchi K., Than N.G., Diaz P., Ahmed M.S., Tamura I., Nanovskaya T., Morales-Prieto D.M., Desoye G., Boeuf P., Tomi M., Roberts C.T., Daoud G., Nobuzane T., Saffery R., Komatsu R., Aleksunes L.M., Tamura K., Illsley N.P., Lao T., Chung M.K., Golos T.G.   +20 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Si-Based Hydrogen-Producing Nanoagent Protects Fetuses From Miscarriage Caused by Mother-to-Child Transmission

Frontiers in Medical Technology, 2021
Mother-to-child transmission of viruses and bacteria increases the risk of miscarriage and various diseases in children. Such transmissions can result in infections and diseases in infants or the induction of an inflammatory immune response through the ...
Noriyoshi Usui, Noriyoshi Usui, Noriyoshi Usui, Noriyoshi Usui, Shogo Togawa, Shogo Togawa, Takuya Sumi, Takuya Sumi, Yuki Kobayashi, Yoshihisa Koyama, Yoshihisa Koyama, Yukiko Nakamura, Yukiko Nakamura, Makoto Kondo, Makoto Kondo, Koh Shinoda, Hikaru Kobayashi, Shoichi Shimada, Shoichi Shimada, Shoichi Shimada   +19 more
doaj   +1 more source

Review: The Placenta is a Programming Agent for Cardiovascular Disease [PDF]

Placenta, 2010
Cardiovascular disease remains the number one killer in western nations in spite of declines in death rates following improvements in clinical care. It has been 20 years since David Barker and colleagues showed that slow rates of prenatal growth predict mortality from ischemic heart disease.
K L, Thornburg, P F, O'Tierney, S, Louey
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

ventolab/Placenta-Infection: Placenta-Infection

<h1>Placenta-Infection</h1> <p>Repository dedicated to harbour all the scripts used to analyse the data product of our Placenta Infection experiments.</p ...
Elias R Ruiz-Morales, reginahoo
core   +2 more sources

The Placenta in Sickle Cell Disease

Archives of Pathology & Laboratory Medicine, 2000
A from a 28-year-old, African American, primigravida patient with sickle cell trait was received for routine pathologic examination. Prior to her current pregnancy, this patient had been admitted 3 times during adolescence for sickle cell crises and had documented retinopathy. The pregnancy was uneventful. Blood tests revealed a normochromic normocytic
Liron Pantanowitz, Robert Schwartz, Karoly Balogh   +2 more
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus

, 2016
Publisher Copyright: © 2016 Elsevier Ltd. All rights reserved.The placenta is a vital organ whose function in diseases of pregnancy is altered, resulting in an abnormal supply of nutrients to the foetus.
Araos, Joaquín, Universidad San Sebastián, Leiva, Andrea, Barros, Eric, Sanhueza, Carlos, Pardo, Fabián, Sobrevia, Luis, Salsoso, Rocío, Gutiérrez, Jaime, Sáez, Tamara, Silva, Luis, Toledo, Fernando   +11 more
core   +1 more source