Results 161 to 170 of about 854,609 (354)
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt +2 more
wiley +1 more source
Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]
, 2003 Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa +3 more
core +1 more source
Impact of Nutrition on Sphingolipid‐Regulated Physiology: A Review
Molecular Nutrition &Food Research, EarlyView.Sphingolipids (SLs) play a role in multiple, if not all physiological processes. This review summarizes the current knowledge on SLs and their role in (patho‐) physiological processes with special regard to dietary and transgenerational effects. Image was created with BioRender.com.
Jonas Voß +2 more
wiley +1 more source
Brazilian Journal of Cardiovascular Surgery, 1992 O aumento da resistência vascular placentáriae distúrbios de trocas gasosas freqüentemente ocorrem após a circulação extracorpórea (CEC) fetal. A utilização de um circuito convencional de CEC que exclua a placenta da circulação através do clampeamento ...
Renato S Assad +4 more
doaj
ChemistryOpen, EarlyView.This work investigates the selective inhibition of MAO enzymes by varying the substitution of electron‐withdrawing and donating groups on the phenyl rings of tetrahydropyridines (4 a–4 o). Compounds 4 l and 4 n exhibit promising IC50 values of 0.40±0.05 and 1.01±0.03 μM against MAO‐A and MAO‐B, respectively.
Obaid ur Rehman Khan +10 more
wiley +1 more source
Maternal–foetal immune rejection: parallels between placental CHI and allograft rejection†
The Journal of Pathology, EarlyView.Abstract Chronic histiocytic intervillositis (CHI) is a rare placental inflammatory lesion increasingly viewed through maternal–foetal immune rejection. In this invited commentary, we discuss how a recent study bolsters the paradigm that CHI represents maternal immune rejection of the semi‐allogeneic foetus, analogous to antibody‐mediated rejection in ...
Panicos Shangaris +1 more
wiley +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
Prenatal Diagnosis, EarlyView.ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
DIAGNOSIS AND PREVENTION OF PREECLAMPSIA USING ULTRASOUND DOPPLER STUDIES AND HEMOSTASIS PARAMETERS
Мать и дитя в Кузбассе, 2018 The aim of the research – early diagnosis and prevention of preeclampsia using ultrasound doppler studnd hemostasis parameters, including hereditary thrombophilia and antiphospholipid antibodies. Materials and methods. All women were examined by doppler
Нарт Фарук Кунешко +2 more
doaj
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
Prenatal Diagnosis, EarlyView.ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source