Results 21 to 30 of about 657,935 (241)

Effects and mechanisms of action of sildenafil citrate in human chorionic arteries

Reproductive Biology and Endocrinology, 2009
Objectives Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine growth retardation and for ...
Lynch Tadhg, O'Toole Daniel, Maharaj Chrisen H, Carney John, Jarman James, Higgins Brendan D, Morrison John J, Laffey John G   +7 more
doaj   +1 more source

Transcribed var genes associated with placental malaria in Malawian women [PDF]

, 2006
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-infected erythrocytes isolated from placentas is important for attempts to develop a pregnancy-specific malaria vaccine.
Choong, Ee Ken, Boysen, Katja, Molyneux, Malcolm E, Caragounis, Aphrodite, Duffy, Michael F, Healer, Julie, Rowe, J Alexandra; id_orcid, Rogerson, Stephen J, Noviyanti, Rintis, Brown, Graham V, Kyriacou, Helen M   +10 more
core   +1 more source

Comparison of normal and pre-eclamptic placental gene expression: a systematic review with meta-analysis [PDF]

, 2016
Pre-eclampsia (PE) is a serious multi-factorial disorder of human pregnancy. It is associated with changes in the expression of placental genes. Recent transcription profiling of placental genes with microarray analyses have offered better opportunities
O Brew, O. Brew (3079515), Sullivan, Mark H.F., Brew, Obed, Sullivan, Mark, FH, M H F Sullivan, Brew, O, Woodman, Anthony, Sullivan, MH, A Woodman, M. H. F. Sullivan (3079518), A. Woodman (3079521), Woodman, A   +12 more
core   +1 more source

Sex differences in placental circulation [PDF]

, 2020
Sexual dimorphism in placental morphology and function has increasingly been acknowledged. The differences in adaptation to the intrauterine environment and in perinatal/neonatal outcomes between the sexes has been well described.
Widnes, Christian
core   +1 more source

Use of sildenafil citrate in cases of intrauterine growth restriction (IUGR); a prospective trial

Taiwanese Journal of Obstetrics & Gynecology, 2018
Objective: Intrauterine growth restriction (IUGR) is one of the most serious complications of pregnancy. Up to date, there is no evidence of achieving antenatal treatment of IUGR with abnormal placentation.
Mohammed Maged, Alaa Wageh, Maher Shams, Abdlgawad Elmetwally   +3 more
doaj   +1 more source

Longitudinal determination of serum placental protein 13 during development of preeclampsia [PDF]

, 2008
Objective: To determine maternal serum placental protein 13 (PP13) in normal pregnancy and preeclampsia. Methods: A prospective, longitudinal study with 41 normal pregnant women, 18 cases with preterm delivery or cervix insufficiency and 4 with ...
Neumaier-Wagner, Peruka, Huppertz, Berthold, Sammar, Marei, Chefetz, Ilana, Meiri, Hamutal, Bartz, Clemens, Huppertz, B;Sammar, M;Chefetz, I;Neumaier-Wagner, P;Bartz, C;Meiri, H   +6 more
core   +1 more source

Prenatal endotoxemia and placental drug transport in the mouse: placental size-specific effects. [PDF]

PLoS ONE, 2013
Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein (P-gp--Abcb1a/b) and breast cancer resistance protein (BCRP--Abcg2).
Enrrico Bloise, Manzerul Bhuiyan, Melanie C Audette, Sophie Petropoulos, Mohsen Javam, William Gibb, Stephen G Matthews   +6 more
doaj   +1 more source

Inflammatory Cytokines in Maternal Circulation and Placenta of Chromosomally Abnormal First Trimester Miscarriages [PDF]

, 2012
The impact of abnormal placental karyotype on the inflammatory response within the villous tissue and peripheral circulation of women with miscarriage was evaluated.
Jean Calleja-Agius, Calleja-Agius, Jean, Jauniaux, Eric R.M., Shanthi Muttukrishna, Eric Jauniaux, Muttukrishna, Shanthi   +5 more
core   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Comparing placentas from normal and abnormal pregnancies [PDF]

, 2010
This report describes work carried out at a Mathematics-in-Medicine Study Group. It is believed that placenta shape villous network characteristics are strongly linked to the placenta’s efficiency, and hence to pregnancy outcome.
Kritz, M., Stechi, A., Siggers, J., Preedy, Katharine, Klika, V., Cotter, SL, Gallimore, L., Greenhalgh, David, Kennedy, S., Whittaker, R., Pu, I., Nelson, P., Heazell, Alexander   +12 more
core   +4 more sources