Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal-fetal exchange interface. [PDF]
Proc Natl Acad Sci U S A, 2020 AbstractIn utero mammalian development relies on the establishment of the maternal–fetal exchange interface, which ensures transportation of nutrients and gases between the mother and the fetus. This exchange interface is established via development of multinucleated syncytiotrophoblast cells (SynTs) during placentation.
Bhattacharya B +11 more
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PLoS ONE, 2020 Human fetal thermoregulation, maternal-fetal heat exchange, and the role of the umbilical cord in these processes are not well understood. Ethical and technical limitations have restricted current knowledge to animal studies, that do not reflect human ...
Dorothea Kasiteropoulou +2 more
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Aquaporins in development – a review [PDF]
Reproductive Biology and Endocrinology, 2005 Water homeostasis during fetal development is of crucial physiologic importance. It depends upon maternal fetal fluid exchange at the placenta and fetal membranes, and some exchange between fetus and amniotic fluid can occur across the skin before full ...
Wintour E Marelyn, Liu Huishu
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The GATA transcriptional program dictates cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development. [PDF]
Proc Natl Acad Sci U S AThe placenta establishes a maternal–fetal exchange interface to transport nutrients and gases between the mother and the fetus. Establishment of this exchange interface relies on the development of multinucleated syncytiotrophoblasts (SynT) from trophoblast progenitors, and defect in SynT development often leads to pregnancy failure and impaired ...
Ghosh A +8 more
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Placental Development and Pregnancy-Associated Diseases
Maternal-Fetal Medicine, 2022 . Serving as the interface between the fetal and maternal environments during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of maternal health.
Xin Yu +6 more
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Uptake and release of amino acids in the fetal-placental unit in human pregnancies. [PDF]
PLoS ONE, 2017 OBJECTIVES:The current concepts of human fetal-placental amino acid exchange and metabolism are mainly based on animal-, in vitro- and ex vivo models.
Maia Blomhoff Holm +9 more
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Maternal Oxygen Administration during Labor: A Controversial Practice
Children, 2023 Oxygen administration to the mother is commonly performed during labor, especially in the case of a non-reassuring fetal heart rate, aiming to increase oxygen diffusion through the placenta to fetal tissues.
Isabella Abati +5 more
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Omics Approaches to Study Formation and Function of Human Placental Syncytiotrophoblast
Frontiers in Cell and Developmental Biology, 2021 Proper development of the placenta is vital for pregnancy success. The placenta regulates exchange of nutrients and gases between maternal and fetal blood and produces hormones essential to maintain pregnancy.
Adam Jaremek +4 more
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Placental development and preeclampsia
生物医学转化, 2022 Serving as the interface between the fetal and maternal environment during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of pregnancy.
Zhu Yuelin +3 more
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Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110$\alpha$ signaling to modify placental resource allocation [PDF]
, 2016 Pregnancy success and life-long health depend on a cooperative interaction between the mother and the fetus in the allocation of resources. As the site of materno-fetal nutrient transfer, the placenta is central to this interplay; however, the relative ...
Sferruzzi-Perri, Amanda +3 more
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