Results 121 to 130 of about 403,052 (287)

El tema del placer en Platón [PDF]

open access: yes, 1995
The author sees an evolution of the theory of pleasure in different dialogues of Plato. Martos is aware of the contradictions of this theory in the course of Plato's philosophical development and he says that Aristotle tried to reconcile these ...
Martos-Montiel, Juan Francisco
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Solar engine [PDF]

open access: yes, 1982
A solar engine is disclosed in which a fluid, which is first heated and then cooled, forces a piston outward as the fluid is heated, and then draws the piston inward as the fluid is cooled. The piston is connected to a shaft and produces work as it moves
Jensen, R. N.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

La formación musical como pasión comunicativa = The musical education as communicative passion

open access: yesEducação, 2007
The article is written in dissidence and disagreement with the symbolic universe of modernity (concerning the sciences, technology, experts, virtuosi and professionals). It tries to present based on the sociological imagination, discoursive resources and
Placer, Fernando González
doaj  

Health Status of the Uninsured: Opportunities for Improvement [PDF]

open access: yes, 2004
Provides estimates of the geographic variations in the rates of self-reported fair or poor health status, asthma, and hypertension among uninsured children and adults in ...
Carolyn A. Mendez-Luck   +4 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Many Uninsured Children Qualify for Medi-Cal or Healthy Families [PDF]

open access: yes, 2004
Examines the public health insurance eligibility of children in California who did not have health insurance coverage for some or all of the year in 2002, to highlight the geographic variations in children's uninsured eligibility ...
Alek Sripipatana   +6 more
core  

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