Results 51 to 60 of about 318,051 (294)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Subrecent Movements near Ljubljana
Geologija, 2004 At the eastern margin of the Ljubljansko barje (Ljubljana moor) smaller faults can be seen along which part or the whole colluvial cover is displaced.
Ladislav Placer
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Place of Disaster Topics in the Textbooks from Beginning of the Republic to Present [PDF]
, 2023 Bahadır Kilcan, Şeyma Çakir
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
IMPLEMENTAÇÃO DE UM CURRÍCULO COM MUDANÇA RADICAL: SENTIMENTOS DE PRAZER E SOFRIMENTO
Cogitare Enfermagem, 2005 Apresente pesquisa teve como objetivo verificar se as enfermeiras docentes vivenciam sentimentos de prazer e de sofrimento gerados no trabalho, frente à implementação de uma mudança curricular radical.
Júlia Trevisan Martins +1 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
COMPARISON OF PLATINUM GROUP MINERALS FROM ELUVIAL-DELUVIAL PLACER OF THE SVETLY BOR CLYNOPIROXENITE-DUNITE MASSIF (CENTRAL URALS) [PDF]
Минералогия, 2017 Morphology and composition of platinum group minerals (PGMs) from loose sediments of eluvial-deluvial placer of the Svetly Bor clinopyroxenite-dunite massif are studied.
R.S. Palamarchuk +4 more
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source