Results 51 to 60 of about 404,483 (304)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Principles of the tectonic subdivision of Slovenia
Geologija, 2008 New tectonic subdivision of the junction region between Alps and Dinarides which incorporates Eastern Alps, Southern Alps, Dinarides, Pannonian basin and Adriatic-Apulia foreland is described in this article.
Ladislav Placer
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Petrogeochemistry and Zircon U-Pb Age of Nephrite Placer Deposit in Xiuyan, Liaoning
Yankuang ceshi, 2019 BACKGROUND The Xiuyan placer nephrite is located in the Xiyu gully, Baisha river valley and terrace, located in Xiuyan, Liaoning Province. Currently, the primary nephrite in the Xiyu gully is regarded as the Xiuyan placer nephrite's primary deposit ...
ZHENG Fen, LIU Yan, ZHANG Hong-qing
doaj +1 more source
Fifth annual conference on Alaskan placer mining [PDF]
, 1983 An abridged format of papers, presentations and addresses given during the 1983 conference held on March 30-31, 1983 compiled and edited by Bruce W. Campbell, Jim Madonna, and M. Susan Husted.Partial funding was provided by the Carl G.
Campbell, B.W. +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
On the strucure of Sovič above Postojna
Geologija, 1995 The author maintains that the structure of the Sovič hill above Postojna with its surroundings is structurally a repetition of the structure of the Nanos, Hrušica and Trnovski gozd mountains.
Ladislav Placer
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Structural curiosity of the northern Istria
Geologija, 2005 In northern Istria certain structural particularities exist that till now were not explained,and some of them not even known. They are all associated with underthrusting of the Adriatic microplate (Istra) under the Dinarides.
Ladislav Placer
doaj
Известия высших учебных заведений: Геология и разведка, 2019 About 1400 placers and several dozens of ore gold deposits are known in the Amur gold-bearing province. Placers are to a large degree worked out, so the future of the province is seen to be in the discovery of the new gold deposits.
V. A. Stepanov
doaj +1 more source