Results 71 to 80 of about 403,052 (287)

IMPLEMENTAÇÃO DE UM CURRÍCULO COM MUDANÇA RADICAL: SENTIMENTOS DE PRAZER E SOFRIMENTO

open access: yesCogitare Enfermagem, 2005
Apresente pesquisa teve como objetivo verificar se as enfermeiras docentes vivenciam sentimentos de prazer e de sofrimento gerados no trabalho, frente à implementação de uma mudança curricular radical.
Júlia Trevisan Martins   +1 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

An evaluation of the post-ignition unblocking behavior of solid propellant aft-end ignition systems Final report [PDF]

open access: yes
Determining postignition interactions between igniter and main motor flow by aft-end heated air simulation of solid propellant ...
Fitch, R. E.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Natural revegetation of placer mined lands of interior Alaska II [PDF]

open access: yes, 1980
To the uninitiated eye an aerial photo of Fairbanks’ surrounding area includes patches of what might appear to be the channels left by the workings of a bark beetle grub.
McKendrick, J.D., Neiland, B.J., and Holmes, K.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

COMPARISON OF PLATINUM GROUP MINERALS FROM ELUVIAL-DELUVIAL PLACER OF THE SVETLY BOR CLYNOPIROXENITE-DUNITE MASSIF (CENTRAL URALS) [PDF]

open access: yesМинералогия, 2017
Morphology and composition of platinum group minerals (PGMs) from loose sediments of eluvial-deluvial placer of the Svetly Bor clinopyroxenite-dunite massif are studied.
R.S. Palamarchuk   +4 more
doaj  

Asco y belleza: hacia el deshielo de una relación estética

open access: yesEnrahonar: Quaderns de Filosofia, 2019
Este trabajo se enmarca en la tendencia de la estética actual a restituir, incluso dignificar, las llamadas «emociones negativas», en especial el asco, despreciado en la tradición estética moderna por la imposibilidad de reconciliarlo con el placer y ...
María Jesús Godoy Domínguez
doaj   +1 more source

A Summary of gold fineness values from Alaska placer deposits [PDF]

open access: yes, 1981
This report is the first in a series of publications by the Mineral Industry Research Laboratory and the Alaska Division of Geological and Geophysical Surveys under a special appropriation by the Alaska State Legislature to the School of Mineral Industry
Hawkins, D.B., Metz, P.A.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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