Results 71 to 80 of about 1,590 (296)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
E3S Web of Conferences, 2018 The influence of two most important factors determining gold losses during mining of alluvial deposits is considered. They include the granulometric composition of sands and the initial gold content in them.
Mirzekhanov Gadzhi, Mirzekhanova Zoya
doaj +1 more source
Method for Revealing Placer Gold Source
Горные науки и технологии, 2019 Material characteristics of placer gold and geological and geomorphological features of placercontaining watercourses allow revealing the type of source that formed the placer.
O. V. Vladimirtseva
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Compositional Variations and Genesis of Sandy-Gravel Ferromanganese Deposits from the Yōmei Guyot (Holes 431, 431A DSDP), Emperor Ridge [PDF]
, 2019 This research presents results characterizing the mineral and chemical composition of ferromanganese (Fe-Mn) deposits from Yōmei Guyot (Holes 431 and 431A), recovered during the Deep-Sea Drilling Project (DSDP) Leg 55 R/V “Glomar Challenger”.
Pavel Mikhailik +4 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Global zirconium market as a critical mineral raw material
Горные науки и технологииThis study addresses the growing recognition of zirconium raw materials as a critical mineral resource in most industrialized countries and the need for a comprehensive assessment of the complex global zirconium market.
G. Yu. Boyarko, L. M. Bolsunovskaya
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Provenance, routing and weathering history of heavy minerals from coastal placer deposits of southern Vietnam [PDF]
, 2018 Heavy mineral rich sands along the coastal margin of southern Vietnam often contain commercial deposits of ilmenite and zircon but their origin is unknown.
Nguyen, H. +3 more
core +1 more source