Results 81 to 90 of about 1,590 (296)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Geochemical classification of placer and lode gold deposits within the Northern Dome Rock Mountains of the Quartzsite mining district, AZ [PDF]
, 2012 In this study the geochemistry and distribution of placer and lode gold deposits of the northern Dome Rock Mountains near Quartzsite, Arizona wre studied.
Velasquez, Christina Marie Lopez
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Status of development orientations for mining titanium placers in Vietnam
Горные науки и технологии, 2016 Vietnam has potential reserves of titanium placers, located mainly along the coast of the Middle spreading across provinces from Thanh Hoa to Ba Ria – Vung Tau.
Xuan Nam Bui , Si Giao Ho
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Nephrite placers types of Kunlun and adjacent Tarim depression, China
Известия высших учебных заведений: Геология и разведка, 2015 Preconditions of nephrite placers formation in the Central Kunlun mountains and adjacent Tarim depression are considered in Russian literature for the first time: the presence of the primary deposits in metasomatic rocks localized in alpine-type ...
P. A. Ignatov, Chjao Hen
doaj +1 more source
Mineralogical and Geochemical Characteristics of Banded Agates from Placer Deposits: Implications for Agate Genesis. [PDF]
ACS Omega, 2022 Shen M, Lu Z, He X.
europepmc +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Chemical composition as an indicator of ilmenite genesis and titanium raw material quality
Мінеральні ресурси УкраїниThe study focuses on the chemical composition of ilmenite from various geological settings, including primary and placer deposits, weathering profiles, river and marine sediments, and mud volcanoes.
A. O. Polietnova
doaj +1 more source