Results 101 to 110 of about 10,534 (304)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Cancellation and Uncertainty Aversion on Limit Order Books [PDF]

open access: yes
This paper models limit order books where each trader is uncertain of the underlying distribution in the asset's value to others. If this uncertainty is rapidly resolved, eeting limit orders are submitted and quickly cancelled.
Jeremy Large
core  

Surveying the Alentejo continental shelf for minerals and Quaternary environmental changes: preliminary results of the MINEPLAT project survey [PDF]

open access: yes, 2017
The tectonic uplift of South Portugal in the last 5 Million years (My) was firstly identified on the basis of morphologic criteria by Mariano Feio (1952, “The evolution of the relief of Baixo Alentejo and Algarve”, transl.).
Brito, Pedro   +4 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

PLACER DEPOSITS OF THE RUSSIAN ARCTIC AND WAYS OF DEVELOPMENT [PDF]

open access: yesМинералогия, 2017
Placer deposits of gold, platinoids, tin, diamonds, rare metals and the titan are known in the Arctic region of Russia. Many of the objects are exploitated already more than half a century and so far are in large part developed, while the remained ...
A.V. Lalomov
doaj  

Research and development for the Rare Earth Element supply chain in Europe. [PDF]

open access: yes, 2017
This brochure is a product of the EURARE project, which was funded by the European Commission’s Seventh framework Programme to provide the basis upon which Europe could develop a secure supply of the rare earth elements (REE).
Deady, Eimear   +2 more
core  

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Managing in situ gold concentrations in placers [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2015
In studying of the in situ gravitational concentration process part feature for placer, the technological ability to transform the in situ massif placer structure is evident.
Alexandr Mikhailov
doaj  

Computer program for analysis of split-Stirling-cycle cryogenic coolers [PDF]

open access: yes, 1983
A computer program for predicting the detailed thermodynamic performance of split-Stirling-cycle refrigerators has been developed. The mathematical model includes the refrigerator cold head, free-displacer/regenerator, gas transfer line, and provision ...
Brown, M. T., Russo, S. C.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy