Results 111 to 120 of about 1,640 (307)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Arizona Gold Placers and Placering

, 1932
The first publication of the Arizona Bureau of Mines on Arizona Gold Placers was written by Mr. M. A. Allen, then geologist with the Bureau, and appeared in 1922 as Bulletin 118.
Wilson, E.D., Tenney, J.B.
core  

SEASHORE AND OFFSHORE AMBER­SUCCINITE PLACERS IN UKRAINE

Геологія і корисні копалини Світового океану, 2019
The article speaks about the key influence of the sea basin on the formation of amber­succinite as a mineral and its deposits as the first intermediate collectors.
Victor Matsui, Uliana Naumenko
doaj   +1 more source

Construction Accidents in Spain: Implications for an Aging Workforce. [PDF]

Biomed Res Int, 2022
Fontaneda I, Camino López MA, González Alcántara OJ, Greiner BA.   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Tin Bearing Granites and Tin Placers in Bangka and Billiton Islands in Indonesia [PDF]

, 1973
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。The tin in Indonesia is mainly exploited from placers containing cassiterite. Chemical analysis by the author made clear that mother rocks which liberate the placers belong to the tin granites of the Collision type ...
金山, 清一
core  

User-centered design of central venous access device documentation. [PDF]

JAMIA Open, 2022
Kandaswamy S, Gill A, Wood S, Mckay L, Hike J, Popkin M, Ray E, Maude H, Johnston C, White T, Orenstein E.   +10 more
europepmc   +1 more source

Placer formation and placer minerals

Ore Geology Reviews, 2006
Gerhard Els, Pat Eriksson
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source