Results 81 to 90 of about 305,652 (296)

Ficción, placer y desarrollo

open access: yesChasqui, 1993
Este ensayo analiza las experiencias de la telenovela educativa, define las estrategias y condiciones necesarias para su producción exitosa. Los autores describen el método que Miguel Sabido desarrolló desde Televisa en México y la posterior adaptación de ese modelo en la India y Kenia. En este modelo los valores y creencias culturales que canalizan la
Rogers, Everett   +2 more
openaire   +4 more sources

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

A Grooved Axe in a Strange Place [PDF]

open access: green, 1893
Harvey B. Bashore
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

PLACER DEPOSITS OF THE RUSSIAN ARCTIC AND WAYS OF DEVELOPMENT [PDF]

open access: yesМинералогия, 2017
Placer deposits of gold, platinoids, tin, diamonds, rare metals and the titan are known in the Arctic region of Russia. Many of the objects are exploitated already more than half a century and so far are in large part developed, while the remained ...
A.V. Lalomov
doaj  

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

Managing in situ gold concentrations in placers [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2015
In studying of the in situ gravitational concentration process part feature for placer, the technological ability to transform the in situ massif placer structure is evident.
Alexandr Mikhailov
doaj  

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