Results 81 to 90 of about 313,977 (292)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Terrigenous Tertiary Gold Bearing Strata: World Distribution, Economic Significancy and Modern Placer Formation Capacity

open access: yesRussian Journal of Earth Sciences
The article is dedicated to estimation of tertiary terrigenous strata role in world gold mining. Localization peculiarities of tertiary gold deposits and their placers were examined.
Vladimirceva Ol'ga   +3 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

PLACER DEPOSITS OF THE RUSSIAN ARCTIC AND WAYS OF DEVELOPMENT [PDF]

open access: yesМинералогия, 2017
Placer deposits of gold, platinoids, tin, diamonds, rare metals and the titan are known in the Arctic region of Russia. Many of the objects are exploitated already more than half a century and so far are in large part developed, while the remained ...
A.V. Lalomov
doaj  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Managing in situ gold concentrations in placers [PDF]

open access: yesInternational Journal of Mining and Geo-Engineering, 2015
In studying of the in situ gravitational concentration process part feature for placer, the technological ability to transform the in situ massif placer structure is evident.
Alexandr Mikhailov
doaj  

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