Results 41 to 50 of about 3,781 (217)

Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif‐mediated interactions

Protein Science, Volume 32, Issue 7, July 2023., 2023
Abstract The interaction between the transcription factor p53 and the ubiquitin ligase MDM2 results in the degradation of p53 and is well‐studied in cancer biology and drug development. Available sequence data suggest that both p53 and MDM2‐family proteins are present across the animal kingdom.
Filip Mihalič, Emma Åberg, Pouria Farkhondehkish, Niels Theys, Eva Andersson, Per Jemth   +5 more
wiley   +1 more source

Palaeobiology and taphonomy of the rangeomorph Culmofrons plumosa

Palaeontology, Volume 66, Issue 4, July/August 2023., 2023
Abstract The deep marine Ediacaran fossil record of Avalonia is dominated by the Rangeomorpha, a clade characterized by up to four orders of fractal‐like branching. Despite their abundance, morphological diversity and the recent increase in Ediacaran studies, aspects of their palaeobiology, palaeoecology and phylogenetic position in the tree of life ...
Giovanni Pasinetti, Duncan McIlroy
wiley   +1 more source

Concatenated analysis sheds light on early metazoan evolution and fuels a modern "urmetazoon" hypothesis. [PDF]

PLoS Biology, 2009
For more than a century, the origin of metazoan animals has been debated. One aspect of this debate has been centered on what the hypothetical "urmetazoon" bauplan might have been.
Bernd Schierwater, Michael Eitel, Wolfgang Jakob, Hans-Jürgen Osigus, Heike Hadrys, Stephen L Dellaporta, Sergios-Orestis Kolokotronis, Rob Desalle   +7 more
doaj   +1 more source

Molecular signatures for sex in the Placozoa [PDF]

Proceedings of the National Academy of Sciences, 2005
Placozoans, the simplest free-living animals, have never been observed to reproduce sexually. Here, we describe molecular evidence for sexual reproduction within one clade of the Placozoa. In a population sample of 10 individuals, within-individual and overall nucleotide diversity were similar to each other and consistent with levels observed in ...
Ana Y, Signorovitch, Stephen L, Dellaporta, Leo W, Buss   +2 more
openaire   +2 more sources

Study of NIT domain‐containing chemoreceptors from two global phytopathogens and identification of NIT domains in eukaryotes

Molecular Microbiology, Volume 119, Issue 6, Page 739-751, June 2023., 2023
NIT sensor domains were found in 19 eukaryotic and 30 bacterial phyla and formed part of 7 receptor families that generate a variety of different responses, such as chemotaxis, transcriptional regulation or homeostasis of second messenger levels.
Elizabet Monteagudo‐Cascales, Álvaro Ortega, Félix Velando, Bertrand Morel, Miguel A. Matilla, Tino Krell   +5 more
wiley   +1 more source

RNA interference in marine and freshwater sponges [PDF]

, 2011
Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon, Danka, Elizabeth S., Haen, Karri M., Hammel, Jörg U., Hill, April L., Hill, Malcolm S., Knight, Scott W., Lavrov, Dennis V., Nickel, Michael, Posfai, Dora, Rivera, Ajna S., Winters, Ian P., Wörheide, Gert   +12 more
core   +1 more source

The role of systematics for understanding ecosystem functions: Proceedings of the Zoologica Scripta Symposium, Oslo, Norway, 25 August 2022

Zoologica Scripta, Volume 52, Issue 3, Page 187-214, May 2023., 2023
Abstract On 25 August 2022, the Zoologica Scripta ‐ An International Journal of Systematic Zoology and the Norwegian Academy of Sciences and Letters arranged a symposium entitled ‘The role of systematics for understanding ecosystem functions’ in the Academy's premises in Oslo, Norway. The symposium aimed at offering a forum for exploring and discussing
Lutz Bachmann, Jan Beermann, Thomas Brey, Hugo J. de Boer, Jennifer Dannheim, Bente Edvardsen, Per G. P. Ericson, Kevin C. Holston, Veronika A. Johansson, Paul Kloss, Rebecca Konijnenberg, Karen J. Osborn, Paula Pappalardo, Hendrik Pehlke, Dieter Piepenburg, Torsten H. Struck, Per Sundberg, Stine Svalheim Markussen, Katharina Teschke, Maarten P. M. Vanhove   +19 more
wiley   +1 more source

The evolution of metazoan extracellular matrix [PDF]

, 2011
The modular domain structure of extracellular matrix (ECM) proteins and their genes has allowed extensive exon/domain shuffling during evolution to generate hundreds of ECM proteins.
Adams, Aouacheria, Ball, Barros, Bentley, Bergmeier, Boute, Chapman, Chiquet-Ehrismann, Couchman, Dehal, Engel, Ewan, Exposito, Exposito, Fahey, Gazave, Heino, Hohenester, Huhtala, Hutter, Huxley-Jones, Hynes, Hynes, Hynes, Hynes, King, King, Knack, Martindale, Merline, Myllyharju, Naba, Ozbek, Patthy, Philippe, Philippe, Pick, Putnam, Putnam, Ricard-Blum, Richard O. Hynes, Robertson, Sadler, Schaefer, Schierwater, Sebé-Pedrós, Shalchian-Tabrizi, Srivastava, Srivastava, Tucker, Wada, Whittaker, Whittaker, Yurchenco, Zhang   +55 more
core   +1 more source

Placozoan fiber cells: mediators of innate immunity and participants in wound healing

Scientific Reports, 2021
Placozoa is a phylum of non-bilaterian marine animals. These small, flat organisms adhere to the substrate via their densely ciliated ventral epithelium, which mediates mucociliary locomotion and nutrient uptake.
Tatiana D. Mayorova, Katherine Hammar, Jae H. Jung, Maria A. Aronova, Guofeng Zhang, Christine A. Winters, Thomas S. Reese, Carolyn L. Smith   +7 more
doaj   +1 more source

The evolution of the dystroglycan complex, a major mediator of muscle integrity [PDF]

, 2015
Basement membrane (BM) extracellular matrices are crucial for the coordination of different tissue layers. A matrix adhesion receptor that is important for BM function and stability in many mammalian tissues is the dystroglycan (DG) complex.
Adams, Josephine C, Brancaccio, Andrea
core   +3 more sources