Results 21 to 30 of about 66,539 (264)

Principles of Standardization of Crimean Hemorrhagic Fever Diagnostics and Its Present-Day Peculiarities in the Territory of the Russian Federation

Проблемы особо опасных инфекций, 2012
It is stated that due to epidemic manifestations Crimean hemorrhagic fever (CHF) has recently become one of the most pressing issues in the South of the European part of the Russian Federation, the area where its integrated natural focus is situated.
O. V. Maletskaya, S. A. Shcherbakova, A. P. Beyer, T. V. Taran, B. A. Khapaev, D. M. Bammatov, G. A. Murtazalieva, N. F. Vasilenko, I. N. Sharova, I. G. Karnaukhov, A. N. Kulichenko   +10 more
doaj   +1 more source

MALDI MASS-SPECTROMETRIC ANALYSIS FOR TYPING AND INTRASPECIES DIFFERENTIATION OF CHOLERA VIBRIOS ON THE BASE OF CONSTRUCTION OF THE REFERENCE LIBRARY OF PROTEOMIC PROFILES

Медицинский вестник Юга России, 2014
Purpose: Construction of a personal relevant database on spectra of V. cholerae strains belonging to different biotypes, serological groups and toxigenic levels, which will allow for the identification, differentiation and comparison of bacterial ...
N. R. Telesmanich, V. V. Agafonova, I. A. Chaika, S. O. Seina, O. S. Chemisova, Ye. V. Goncharenko, E. A. Menshikova, M. V. Poleeva   +7 more
doaj   +1 more source

Antibacterial Susceptibility/Resistance of Vibrio cholerae eltor Clinical Strains Isolated in the Caucasus During the 7^th Cholera Pandemic

Антибиотики и Химиотерапия, 2020
The data on antibacterial susceptibility and resistance of Vibrio cholerae eltor phenotypes with different sets of the susceptibility or resistance markers conditioning the outbreaks and sporadic cases of cholera in the Caucasus within 1970-1998 are ...
V. N. Savelyev, B. V. Babenyshev, I. V. Savelyeva, O. V. Vasilyeva, L. V. Guseva, G. M. Grizhebovsky, SH. KH. Kurbanov, B. M. Asvarov, B. A. Batyrova, I. G. Doroshenko, A. D. Antonenko   +10 more
doaj  

Global evolution and phylogeography of Brucella melitensis strains

BMC Genomics, 2018
Background Brucellosis is a bacterial zoonotic disease. Annually in the world more than 500,000 new cases of brucellosis in humans are registered. In this study, we propose an evolutionary model of the historical distribution of B.
Sergey V. Pisarenko, Dmitry A. Kovalev, Anna S. Volynkina, Dmitry G. Ponomarenko, Diana V. Rusanova, Nina V. Zharinova, Anna A. Khachaturova, Lyudmila E. Tokareva, Irina G. Khvoynova, Alexander N. Kulichenko   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Review of Anthrax Situation 2013, the Forecast for 2014

Проблемы особо опасных инфекций, 2014
The analysis of epidemiological and epizootiological situation on anthrax in the Russian Federation and in the world in 2013 is carried out. The forecast of disease for 2014 is presented. Anthrax morbidity in humans in Russia is shown to decrease in 2013
A. G. Ryazanova, E. I. Eremenko, N. P. Buravtseva, L. U. Aksenova, O. I. Tsygankova, E. A. Koteneva, T. M. Golovinskaya, V. V. Voropaev, O. V. Pluzhnikova, A. N. Kulichenko   +9 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Impact of the Present-Day Climate Changes on the Natural Plague Foci Condition, Situated in the Territory of the Russian Federation and Other CIS Countries

Проблемы особо опасных инфекций, 2013
Climate changes determine dynamics of epizootic activity of natural plague foci in the XX and XXI centuries. Obvious shift to continentality in the Northern hemisphere can put an end to inter-epizootic period in lowland steppe and semi-desert natural ...
N. V. Popov, V. E. Bezsmertny, A. I. Udovikov, A. A. Kuznetsov, A. A. Sludsky, A. N. Matrosov, T. V. Knyazeva, Yu. M. Fedorov, V. P. Popov, A. K. Grazhdanov, T. Z. Ayazbaev, S. A. Yakovlev, T. B. Karavaeva, V. V. Kutyrev   +13 more
doaj   +1 more source