Results 31 to 40 of about 51,837 (241)

Application of the Plan-Do-Check-Act cycle for managing immune-related adverse events [PDF]

, 2022
Abstract BackgroundImmune checkpoint inhibitors (ICIs) sometimes cause immune-related adverse events (irAEs), the timing of occurrence of which is difficult to predict. We created a system to safely manage the patients treated with ICIs who visit hospital during an emergency.MethodsWe utilized the Plan-Do-Check-Act (PDCA) cycle method to ...
Satoshi Hibi, Yuko Shirokawa, Kengo Nanya, Yuko Kato, Nobuto Ito, Takae Kataoka, Takashi Yoshida, Yoshiaki Marumo, Satoshi Kayukawa, Shu Yuasa, Kenji Ina   +10 more
openaire   +1 more source

Mobile pre-hospital care reorganization during the COVID-19 pandemic: experience report

Revista Brasileira de Enfermagem
Objective: To describe the reorganization of Belo Horizonte’s Mobile Emergency Care Service during the new coronavirus pandemic using the Plan Do-Check-Act quality tool. Methods: Descriptive study, of the experience report type, on the reorganization of
Daniela Aparecida Morais, Cíntia Maria Guedes de Moraes, Karina Mara de Souza, Roger Lage Alves   +3 more
doaj   +2 more sources

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

A Model of Iranian Administrative System Based on Academic and Professional Experts’ Outlook [PDF]

فرایند مدیریت و توسعه, 2023
Purpose: Regarding the challenges of Iran's administrative system, the aim of this research was to develop a suitable model that could consider the various elements of the administrative system and its important approaches.
Sahar Babaei, Reza Vaezi, Ali Asghar Pourezzat, Davood Hosseinpour   +3 more
doaj  

Application of the Plan-Do-Check-Act Cycle for Managing Immune-Related Adverse Events

Journal of Analytical Oncology, 2021
Background: Immune checkpoint inhibitors (ICIs) sometimes cause immune-related adverse events (irAEs), the timing of occurrence of which is difficult to predict. We created a system to safely manage the patients treated with ICIs who visit hospital during an emergency.
Satoshi Hibi, Yuko Shirokawa, Kengo Nanya, Yuko Kato, Nobuto Ito, Takae Kataoka, Takashi Yoshida, Yoshiaki Marumo, Satoshi Kayukawa, Shu Yuasa, Yoshiteru Tanaka, Kenji Ina   +11 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Impact of Pharmacist-Led PDCA Cycle in Reducing Prescription Abandonment: An Action Research from China

Patient Preference and Adherence, 2023
Lisong Lv, Yunfeng Sun, Bo Yang, Chuanwei Xin, Mingwan Zhang Department of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, People’s Republic of ChinaCorrespondence: Chuanwei Xin, Department of Pharmacy, Tongde Hospital of Zhejiang ...
Lv L, Sun Y, Yang B, Xin C, Zhang M
doaj  

IMPLEMENTATION OF RISK MANAGEMENT FOR OUTCOME-BASED LEARNING

Jurnal Eduscience, 2023
This classroom action research discusses the application of risk management in delivering results-based learning. The author uses a conceptual model development approach and examples of application in a course.
Muhammad Rosiawan, Juliani Dyah Trisnawati   +1 more
doaj   +1 more source