Results 41 to 50 of about 51,837 (241)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Implementation of (Plan-Do-Check-Act) Process of Quality and Measuring its Effect on Nurses' Practice of Patient Safety Goals [PDF]

Egyptian Journal of Health Care, 2019
Background: Implementing PDCA (plan- do- check – act) management can improvepatient safety and satisfaction. Head nurse should create and maintain their safety management toincrease the quality of nursing practices regarding patient safety goals practice.
Assist. Prof/Hemat. A. Mostafa, Prof.Dr/ Mona. M. Shazly, Motiaa. F. Seliem   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Facility Management using digital Obeya Room by integrating BIM-Lean approaches – an empirical study

Journal of Civil Engineering and Management, 2018
This paper applies a methodology for interdisciplinary Facilities Management (FM) by alingment between Building Information Modeling (BIM) and Lean. Initially, the literature review of BIM, FM and Lean principles.
Daniel Luiz de Mattos Nascimento, Osvaldo Luiz Gonçalves Quelhas, Marcelo Jasmim Meiriño, Rodrigo Goyannes Gusmão Caiado, Simone D. J. Barbosa, Paulo Ivson   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

La implementación en el nivel operativo del proceso de enfermería The implementation in the operative level of the nursing process

Revista Latino-Americana de Enfermagem, 1999
El mejoramiento continuo es el marco de referencia utilizado como guía del proceso de enfermería por medio del giro del PDCA. (plan, do, check, act). Traducido en VIDA. (visión, implementación, discernimiento, ajuste).
Nora Agnes Vega Villalobos
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Continuous quality improvement: reducing informed consent form signing errors

BMC Medical Ethics, 2023
Background Adherence to ethical guidelines and regulations and protecting and respecting the dignity and autonomy of participants by obtaining a valid informed consent form (ICF) prior to participation in research are crucial; The subjects did not add ...
Tsui-Wen Hsu, Chi-Hung Huang, Li-Ju Chuang, Hui-Chen Lee, Chih-Shung Wong   +4 more
doaj   +1 more source

A Novel Approach for Environmental Management of Dental Practice: The “Plan-Do-Check-Act” Model

, 2022
Background There is increasing awareness of problems associated with global warming but a lack of a systematic approach on how to deliver more environmentally sustainable dental care. A sustainable world aims to ensure that basic needs and quality of life of everyone are met, now and for future generations.
Angela Rovera, Lorenzo Banducci
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source