Results 31 to 40 of about 12,774 (254)
Proceedings, 2020 The purpose of this paper is to establish the specifications of an analysis and evaluation model in the form of a reference framework for the design, development, implementation, periodic evaluation, and continuous improvement of quality management ...
Flaviu Moldovan
doaj +1 more source
Water Policy, 2022 Improving the governance effectiveness of river basin units (RBUs) is often the focus of academic studies. However, the literature on measuring the influencing factors of the river basin governance effectiveness in urban areas is relatively scarce ...
Chang-Yen Lee, Wen-Jung Chang
doaj +1 more source
Application of the Plan–Do–Check–Act Cycle in Shortening the Decision to Delivery Interval Time
Risk Management and Healthcare Policy, 2022 Ming-Na Lu, Bai-Lei Zhang, Qiao-Hong Dai, Xian-Hu Fu Department of Obstetrics and Gynecology, Ningbo Women and Children’s Hospital, Ningbo, 315012, People’s Republic of ChinaCorrespondence: Qiao-Hong Dai, Department of Obstetrics and Gynecology, Ningbo ...
Lu MN, Zhang BL, Dai QH, Fu XH
doaj
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Peningkatan dan Perbaikan dari Temuan Audit External ISO 9001 di LP3I College
Majalah Ilmiah Bijak, 2019 The findings of external audits in order to ensure the implementation of ISO 9001 quality management system at LP3I College for three consecutive years provide benefits in the form of improvement, correction and consistency of the quality management ...
Wiwiet Prihatmadji
doaj +1 more source
Formation and management of safety culture in the railway industry: best practices and strategies
Збірник наукових праць Державного університету інфраструктури та технологій: серія "Транспортні системи і технології", 2023 This article examines the current issue of safety culture in the railway industry, in particular, the formation and development of a safety culture on the railways of Ukraine.
O. Bal
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source