Results 111 to 120 of about 62,891,156 (300)
Formation : "Les Plans de Gestion des Logiciels de la Recherche". Questions et Réponses sur le Modèle PRESOFT et les Plans de Gestion [PDF]
L’objectif de ce document est de reprendre certaines questions qui ont été posées par les participants aux deux formations « Les logiciels de la recherche et les licences : trois visions sur un objet avec un atelier sur les Plans de gestion de logiciels », 1 et 8 juin 2026, https://ligm.univ-eiffel.fr/~teresa/presoft/2026FormationLogicielsRecherche/
openaire +4 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Plan regional de desarrollo del sector agropecuario de la IV region: Anexos
Este documento, contiene los anexos del Plan regional de desarrollo del sector agropecuario de la IV region, los cuales abarca la situación actual y perspectiva de la región en relación a los problemas originados por la escasez de agua; los aportes del ...
Momberg, Alfonso +3 more
core
Plan de aforos. Red secundaria 2000: Jaén
Andalucía. Consejería de Obras Públicas y Transportes; Andalucía. Dirección General de Carreteras; Andalucía. Servicio de Explotación y TecnologíaContiene: Mapa red secundaria 2000.
Andalucía. Consejería de Obras Públicas y Transportes +2 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Bien communiquer sur sa thèse, suite.
Après une brève présentation sur lui-même, Edouard Paulino du Craft (Centre de recherche et d’appui pour la formation et ses technologies, qui travaille à l’ Epfl ) lance le débat : que signifie communiquer sur sa thèse ?
Philippe Heller
doaj
This paper describes two experiments designed to ascertain whether the way in which architectural plans are displayed on a computer screen influences the quality of their correction by humans, and identify the visual exploration strategies adopted in this type of task.
Fleury, Sylvain, Jamet, Eric
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